Exhibitor Tutorial

InSphero Inc. Exhibitor Tutorial: Achieving greater in vitro relevance with screening-compatible, next-generation 3D human disease and organ models

Tuesday, February 6
9:30 AM - 10:15 AM
Location: Room 4

Complex human 3D tissue models for efficacy and toxicity screenings are becoming increasingly prevalent for efficiently de-risking and streamlining the drug discovery process. This tutorial covers the basics of implementing healthy and diseased human 3D microtissue models for applications such as toxicity testing, Steatotic/Fibrotic/NASH liver therapeutic agent efficacy assessments, diabetes modeling, as well as immuno-oncology applications with screening-compatible endpoints. Moreover, we will also address solutions for integrating these tissue models in automation-compatible body-on-a-chip/microphysiological systems. Aspects comprise: 3D microtissue models for disease modeling and efficacy testing, 3D microtissue models for safety testing, 3D microtissue models for target validation, and screening-compatible body-on-a-chip and microphysiological devices.

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Frank Junker

Chief Business Officer
InSphero AG

Serving as Chief Business Officer at InSphero AG, Frank is a life-science professional with more than 15 years industry experience, where he has held various positions in sales & marketing, product management and business development. His experience ranges from bioinformatics, in vitro diagnostics, and cell-culture in mid-sized as well as large corporations. Frank holds a PhD in Molecular Microbiology from ETH Zurich.

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Patrick Guye

Chief Scientific Officer
InSphero AG

The Chief Scientific Officer at InSphero AG, Dr. Guye possesses extensive experience in life sciences, engineering, business innovation & development, operations and new ventures consulting. He has held leadership positions in industry (Sanofi) and academia (Massachusetts Institute of Technology, Princeton University) with a focus on cell therapy, 3D cellular models/organoids, synthetic biology, human stem cells, biologics and small molecules development, and precision genomic engineering. Patrick earned his PhD in Molecular Infection Biology from the University of Basel.

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Olivier Frey

Group Lead Technology & Platforms
InSphero AG

Olivier Frey leads the Technology & Platforms group at InSphero AG, Switzerland. InSphero provides superior biological relevance to in vitro testing with its easy-to-use solutions for production, culture and assessment of organotypic 3D cell culture models. Before joining InSphero, Olivier Frey, was group leader at the Department of Biosystems Science and Engineering of ETH Zurich, Switzerland. In the Bio Engineering Laboratory of Prof. Andreas Hierlemann he was responsible for the development of integrated microfluidic systems for single cell handling and 3D tissue cultures. Included are in particular multi-tissue systems, or so-called “Body-on-a-Chip” configurations based on 3D microtissue spheroids for microtissue culturing, analysis and interaction. Olivier Frey received his Diploma in Mechanical Engineering from ETH Zurich and his Doctoral degree in Micro Engineering from EPF Lausanne, Switzerland, Laboratory (SAMLAB) of Prof. Nico de Rooij.

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Send Email for InSphero Inc. Exhibitor Tutorial: Achieving greater in vitro relevance with screening-compatible, next-generation 3D human disease and organ models