The complexities of assay development, and challenges associated with validating and transferring assays into HTS are well known bottlenecks in the drug discovery process. Industry experts from GSK and TTP Labtech will discuss how they have collaborated in order to address this with the application of a novel liquid handling technology, which can be utilised for both complex, multifactorial assay development experiments as well as large scale, high throughput, drug discovery screening. dragonfly discovery has enabled researchers at GSK to significantly reduce assay development costs and cycle times, through the application of automated design of experiment (DoE), which has led to an improvement in reproducibility and a subsequent increase in assay quality.
Investigator , Screening, Profiling and Mechanistic
Biology UK, GSK
Pete graduated from the University of Newcastle-upon-Tyne, UK with a BSc in Biochemistry, and joined GSK in 2001. He initially worked in the Molecular Screening department carrying out some of the first automated, 1536 HTS assays in GSK, before moving into the assay development and mechanistic biology where he has worked since. Pete has predominantly worked in support of the Epigenetic group within the immune-inflammation therapy area at GSK, leading one drug discovery program and representing his platform department on several other teams. While working at GSK, Pete has achieved a MSc in Structural Biology from Birkbeck College London and is currently working towards a PhD, studying an enzyme involved in Cell wall biosynthesis, at the Francis Crick Institute. Pete is the capability lead for Biochemical systems at GSK and has a keen interest in applying new technologies and approaches to assay development, compound profiling and mechanistic biology.
Director, Product Strategy
Joby's role combines engineering expertise, project, product and account management to aid the design, development and sales of innovative products and solutions for healthcare, pharmaceutical and biotechnology sectors. With a first class honours degree in product design and manufacture from Loughborough University, he has 10 years experience in industrial research and development, project management and sales and marketing. Since joining Labtech, he has been a key engineer and project leader for the development of the mosquito® range of products, which provide precise nanolitre liquid dispensing with zero cross contamination, and has been instrumental in establishing TTP Labtech as an internationally recognised provider of leading-edge technologies for drug discovery and development.
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