Automation and High-Throughput Technologies

Co-development of Instruments and Assays to Optimize Biologically Relevant Screening/Profiling Systems

Wednesday, February 7
11:00 AM - 11:30 AM
Location: 6F

GNF develops and manufactures high throughput drug discovery platforms for both small molecules and biologics. The High Throughput Screening (HTS) and Automated Cellular Profiling (ACP) systems feature high capacity, excellent performance and reliability. The highly integrated systems are complemented by smaller modular systems that allow for rapid reconfiguration and ultimate flexibility. More recently, these systems and devices have been challenged by more complex 3D, physical stimulation, highly multiplexed gene expression/NGS readouts and other phenotypic assays coupled with complex cell sources such as primary and co-cultures. This presentation will highlight several case studies where the co-development of both instruments and assays resulted in unique and powerful solutions.

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Jason Matzen

Automation Engineer
GNF Systems

As an automation engineering with fifteen years of industry experience, Jason Matzen has worked with HTS automation systems his entire career. Starting as a quality control specialist at Aurora Biosciences he learned the landscape of the biotech industry. He transferred to the Genomics Institute of the Novartis Research Foundation (GNF) in early 2002 to run their HTS system. Jason has worked on a variety of screening projects including reporter, target, and phenotypic screens. He has since transitioned to oversee the screening operations at GNF and work with GNF’s engineering group to develop new instrumentation.

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Co-development of Instruments and Assays to Optimize Biologically Relevant Screening/Profiling Systems



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