
Patrick J. O'Shea
Senior Research Scientist
Astrazeneca
Patrick O'Shea is a Senior Scientist in the High Content Biology group within Discovery Sciences at AstraZeneca in Cambridge UK; a multidisciplinary R&D unit with a global remit. The team develops novel phenotypic assays and uses high-content and functional genomic approaches to understand novel biology, provide an early insight into compound toxicity, and to characterize compound mechanism of action in disease relevant models. Prior to joining AstraZeneca, Patrick studied Pharmacology at the University of Leeds. He completed a PhD at Imperial College London, studying the developmental effects of thyroid hormones in bone and cartilage, and was a postdoctoral fellow at Imperial College London and at the National Cancer Institute, NIH.
Presentation(s):
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A high-throughput arrayed CRISPR/Cas9 functional genomics approach to study NF-kB signaling
Tuesday, February 6
11:00 AM – 11:30 AM