Brian E. Cathers
Exec. Director
Celgene
Dr. Cathers is Executive Director and Head of Drug Discovery for the Protein Homeostasis Thematic Center of Excellence at Celgene. Dr. Cathers joined Celgene in 2004 and has led multiple Discovery Projects to successful candidate nominations and IND filings. Prior to Celgene, Dr. Cathers was Director of Enzymology & Biophysical Chemistry at NewBiotics. He generated and led several discovery projects in oncology and infectious diseases. Prior to NewBiotics, Dr. Cathers was a scientist at Axys Pharmaceuticals where he specialized in protease targets (e.g. cathepsins S, B and K) for inflammatory and oncology indications. Dr. Cathers earned his Ph.D. in Medicinal Chemistry from the University of Kansas synthesizing and characterizing novel transition state mimics as inhibitors of HIV protease and was a post-doctoral fellow at the University of Texas in Austin where he trained with Laurence Hurley and Dan Von Hoff working in the areas of G-quadruplex DNA and telomerase.
Presentation(s):
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Targeted Protein Degradation via Redirecting the Action of CRL4 E3 Ligases
Wednesday, February 7
3:00 PM – 3:30 PM