Category: Micro- and Nanotechnologies
Effective single-cell cloning plays an important role in generation of monoclonal antibodies. Within the past years, single-cell technologies especially microfluidic drop-on-demand dispensing have gained increased attention in biopharmaceutical industry. The development and characterization of single-cell deposition with manual image verification that provides greater than 99.99% assurance of clonally-derived cell lines will be discussed.
Mandy Yim– Research Associate, Genentech, South San Francisco, California
South San Francisco, California
Mandy Yim is an innovative upstream cell culture automation specialist at Genentech with 8 years of automated liquid handling, data management, and processes improvement experience to support stable cell line development to produce antibodies in mammalian CHO cells for clinical and manufacturing development.