Category: Biologics Discovery

1192-C - Phytochemical Constituents, in vitro free radicals Scavenging activity and oxidative DNA damage defensive property of methanol extract from Honecrip apple.

Tuesday, February 6, 2018
2:00 PM - 3:00 PM

This research report the qualitative phytochemical constituents and considers the in vitro free radicals scavenging activities based on DPPH, and nitric oxide assays and oxidative DNA damage protection activity of methanol extract from honeycrip apple. The foremost interest for this research was to use standard measures to determine nitric oxide scavenging activity, DPPH-scavenging activity and DNA damage protecting activity to evaluate the antioxidant potential of methanol extract from the apple. Concentrations of apple extracts ranging from 0.02 to 0.10 mg/ml were prepared and mixed with suitable volumes of reagents and the respective absorbances read at the respective wavelength. The results of this study specify that methanol extract of honeycrip apple contain  multiple phytochemical compounds that can expertly protect the body against oxidative stress caused by free radicals and might therefore be used as a source of potent natural antioxidant compounds. The DNA damage defensive potential of the extracts was also revealed, which could be used in cancer inhibition.



Hohai University
Nanjing, Jiangsu, China (People's Republic)

Williams Kweku Darkwah*
Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, Ministry of Education, Environmental Engineering Department, College of Environment, Hohai University, China..
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