Category: High-Definition Biotechnology
The rapidly growing field of single cell analytics seeks to answer questions about cellular diversity in various diseases and developmental processes and can lead to the discovery of novel cell subtypes and stages. The genetic profiling of single cells of cancerous tissue will open up new views to their possible heterogeneity, which might have a significant effect on the treatment of an individual patient.
Higher cell throughputs for single cell sequencing are needed for identification of rare cell types which can lead to better understanding of the cellular heterogeneity. Acoustic dispensing is a powerful method for high precision dosing of assay reagents in very small volumes and is thus ideal also for miniaturization of full length single cell mRNA sequencing reactions. These reagents are expensive, so smaller reaction volumes bring significant savings in reagent costs. In addition acoustic dispensing is touchless reducing the risk of contamination.
Laura Turunen– Laboratory Coordinator, FIMM /High Throughput Biomedic, Helsinki University, Uusimaa, Finland
FIMM /High Throughput Biomedic
Helsinki University, Uusimaa, Finland
Laura Turunen has worked at FIMM High Throughput Biomedicine (HTB) team for eight years as automation specialist and compound manager. She's responsible for the various automated equipment, including various liquid handlers and dispensers, and the compound collections consisting approximately 130 000 compounds from commercial sources. She's also planning and running various projects for users of the HTB lab services.