Supporting Active 3Rs Culture Within Academic Organizations: New Strategies and Tools from the United Kingdom

Tuesday, March 20
4:30 PM - 5:45 PM
Location: Franklin C

Implementation of the 3Rs (replacement, reduction, refinement) is a key component of animal care and use programs. However, there can be challenges to fully applying the 3Rs within the academic sector, as well as a lack of benchmarks to gauge success. This session will demonstrate the importance of developing an institutional framework for supporting the 3Rs that delivers benefits to scientists and animals, and provide new strategies and tools from the United Kingdom's National Centre for the Replacement, Refinement and Reduction of Animals in Research designed to help academic institutions improve and measure their 3Rs engagement and activity. During this session, speakers and attendees will:

Samuel Brod

Science Manager, Animal Welfare and Policy
National Centre for the Replacement, Refinement and Reduction of Animals in Research

Samuel works as a science manager at the UK National Centre for the Replacement Refinement and Reduction of animals where he supports its animal welfare programme and policy initiatives, such as the peer review service. He is a member of the Research Management and Policy Group.

Presentation(s):

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Melanie L. Graham, MPH, PhD

Associate Professor, Department of Surgery; Adjunct Associate Professor, Veterinary Population Medicine; Program Director, Preclinical Research Center
University of Minnesota

Dr. Graham is an Associate Professor in the Departments of Surgery and Veterinary Population Medicine. Dr. Graham is also the Director of the Preclinical Research Center (PCRC) at the University of Minnesota. She earned her M.P.H in Epidemiology from the University of Minnesota and her Ph.D from Utrecht University.  Her research is centered on the development of cell-based therapies for the treatment of diabetes, specifically extrahepatic delivery of islets. Dr. Graham is also widely recognized for her expertise in the characterization and refinement of animal models of chronic disease to enhance translation to the clinic. This work proved pivotal to the first demonstration of successful long-term diabetes reversal after adult pig islet xenotransplant in nonhuman primates. Dr. Graham is serving on the North American 3Rs Consortium Board of Directors, the Academy of Surgical Research Board of Directors, the NIAID Nonhuman Primate Transplantation Tolerance Cooperative, and NIAID Immunobiology of Xenotransplantation Cooperative Research Program. Her research is supported by the State of Minnesota, JDRF, and NIH.

Presentation(s):

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Mark J. Prescott, PhD

Director of Policy and Outreach
National Centre for the Replacement, Refinement and Reduction of Animals in Research

Mark is Director of Policy and Outreach at the UK's national centre for the 3Rs (NC3Rs), where he has worked for over 13 years. He provides strategic oversight of the Centre’s relationships with other research funders and the academic community, including its peer review and advice service, regional staff, and programmes on animal welfare and experimental design. Mark trained as a zoologist and primatologist, and has over 20 years’ research experience in primatology, animal behaviour and animal welfare science. He serves on a number of ethics committees and scientific advisory boards at project, institution, journal and governmental levels.

Presentation(s):

Send Email for Mark Prescott


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