The 3Rs in North America

Tuesday, March 20
3:00 PM - 4:15 PM
Location: Franklin C

There has been a lot of activity surrounding the 3Rs in North America over the last two years. This session will bring together representatives from groups working to advance research and education on the 3Rs. Speakers will discuss how they are breaking down silos and creating collaborative work groups, as well as provide information to attendees on how to get involved in these groups and develop ideas on how research and education in this area can move forward. During this session, speakers and attendees will:

Natalie A. Bratcher, MS

3Rs Scientific Liaison & Animal Welfare Specialist
AbbVie, Inc.

Natalie serves as 3Rs Scientific Liaison and Animal Welfare Specialist within AbbVie’s Office of Animal Welfare. She earned a Master’s degree in Cognitive and Behavioral Sciences from Illinois State University with an emphasis on applied behavior analysis. She spent her first 7 years with Abbott as a neuroscience pharmacologist in the area of CNS diseases research where she was responsible for a number of preclinical in vivo models. Natalie developed a passion for improving research animal welfare and promoting refinement, replacement and reduction of animal use in research, recognizing that there are many opportunities for improving both animal welfare and scientific practices by way of the 3Rs. While an ethical obligation to adopt alternatives when possible exists, researchers have little time to pursue the studies necessary to assess the impact of change that comes with 3Rs implementation. This full time position was proposed and created as a means of achieving research necessary for impact and implementation of various 3Rs initiatives. Working with the Director of Animal Welfare and many scientific mentors across R&D, Natalie serves as an ambassador and scientific liaison to facilitate and communicate all AbbVie’s global 3Rs efforts. In 2013, when Abbott divested the pharmaceutical R&D division, now AbbVie, Natalie took on the additional role of Global Animal Welfare Specialist to support compliance with AbbVie’s Global Animal Welfare Policy, USDA regulations, and AAALAC International expectations by coordinating a global 3rd party supplier oversight program for all contracted animal use.

Natalie values collaborating and building relationships with like-minded professionals. She has served on the PRIM&R planning committee the past two years, is honored to be serving as the Vice President of the newly formed North American 3Rs Collaborative and sits on the steering committee for the Innovation and Quality Consortium’s 3Rs Leadership Group. Her current research interests and collaborations include investigating factors leading to successful social housing of male mice, benefits and 3Rs impact of utilizing digital vivarium technology, and investigating the use of CO2 for refining humane euthanasia in rodents.


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Mark J. Prescott, PhD

Director of Policy and Outreach
National Centre for the Replacement, Refinement and Reduction of Animals in Research

Mark is Director of Policy and Outreach at the UK's national centre for the 3Rs (NC3Rs), where he has worked for over 13 years. He provides strategic oversight of the Centre’s relationships with other research funders and the academic community, including its peer review and advice service, regional staff, and programmes on animal welfare and experimental design. Mark trained as a zoologist and primatologist, and has over 20 years’ research experience in primatology, animal behaviour and animal welfare science. He serves on a number of ethics committees and scientific advisory boards at project, institution, journal and governmental levels.


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Mary Ann Vasbinder, DVM, DACLAM

Head, Global Laboratory Animal Medicine
GlaxoSmithKlinePresident, North American 3Rs Collaborative

Mary Ann Vasbinder serves as the newly appointed Global Head of Laboratory Animal Medicine at GlaxoSmithKline in King of Prussia, Pennsylvania. She worked previously in the Office of Animal Welfare, Ethics and Strategy, serving in two year stints as the Director of Animal External Diligence, Director of Training and Global 3Rs and in internal business monitoring. She served as the Attending Veterinarian at the Research Triangle Park site in North Carolina for 4 years, from 2006-2010. Her current interests lie in building a culture of care and team spirit for animal care and use programs. She is the 2018 President of the North American 3Rs Consortium, which is an organization with a mission to build networks and encourage progress in the 3Rs through a virtual education learning platform. Through collaboration with pharma partners, Mary Ann aspires to join in facilitating a collaborative environment for biomedical research advocacy.


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The 3Rs in North America


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