Scientific and Ethical Considerations in the Use of Gene Editing Techniques to Modify Animal Genomes for Research

Tuesday, March 20
11:15 AM - 12:30 PM
Location: Union E

New gene editing techniques are revolutionizing research with animals. How are they impacting IACUCs? What are the science, policy, and ethical challenges from the widespread use of gene editing technologies (e.g., CRISPR/Cas9, TALENS, and “zinc fingers”)? During this session, speakers and attendees will:

Vincenzo Coppola, MD

Assistant Professor, Cancer Biology and Genetics; Director, Genetically Engineered Mouse Modeling Core, The Ohio State University-Comprehensive Cancer Center
The Ohio State University

Dr. Vincenzo Coppola is an Assistant Professor in the Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University. He is also the Director of the Genetically Engineered Mouse Modeling Core, a shared resource of the Ohio State University and Comprehensive Cancer Center that supports the OSU biomedical scientific community in the generation of genetically modified mouse models to mimic human diseases and study gene functions in vivo.
He is a medical doctor by training with passion for basic science. Throughout his career, he has worked with a variety of mouse models and has more than 20 years of experience in mouse transgenic and knock-out technology. From 2001 to 2010, he was the Head of the Gene Targeting Facility of the Center for Cancer Research of the National Cancer Institute (NIH) in Frederick (MD), and I has contributed to the creation of hundreds of mouse lines using both mouse ES and pronuclear injection technology.
As Director of the GEMMC, he is committed to developing and optimizing new cutting-edge tools for the OSU biomedical community including the powerful CRISPR/Cas9 that allows generating targeted mouse lines in a fraction of the time that was required using traditional technology.

Presentation(s):

Send Email for Vincenzo Coppola

Stephen A. Murray, PhD

Associate Professor
The Jackson Laboratory

Dr. Murray is a developmental biologist and Associate Professor at The Jackson Laboratory in Bar Harbor, Maine USA. He received his Ph.D. in Biochemistry from Boston University School of Medicine in 2003 and was a postdoctoral fellow at The Jackson Laboratory until 2007. His lab studies the genetic networks that regulate neural crest and craniofacial development using both forward and reverse genetic approaches. Now incorporating extensive use of CRISPR/Cas9, he also develops mouse genetic resources for the scientific community, including new models of craniofacial malformations, novel and improved cre driver strains and most recently as one of the principle investigators of the JAX Knockout Mouse Phenotyping Program.

Presentation(s):

Send Email for Stephen Murray


Assets

Scientific and Ethical Considerations in the Use of Gene Editing Techniques to Modify Animal Genomes for Research

Slides

Attendees who have favorited this

Please enter your access key

The asset you are trying to access is locked. Please enter your access key to unlock.

Send Email for Scientific and Ethical Considerations in the Use of Gene Editing Techniques to Modify Animal Genomes for Research