Poster Topical Area: Nutritional Epidemiology

Location: Hall D

Poster Board Number: 772

P20-059 - General and abdominal obesity operate differently as predictors of falls and falls requiring medical care in older women: a population-based cohort study in Spain

Sunday, Jun 10
8:00 AM – 6:00 PM

Objective: The objective of this study was to examine the association of both, general obesity (GO) and abdominal obesity (AO), with falls requiring medical care in a population-based cohort of older adults from Spain.
Methods: A cohort of 2,246 individuals aged ≥ 60, of whom 1,185 were women (52.8%), was established between 2008-10 and followed up throughout 2012. A physical examination was done to obtain information on weight, height, and waist circumference using standardized techniques. Body mass index (BMI) was calculated as weight in kg/(height in m)2, and participants were classified according to the WHO (normal: <25; overweight: 25-29.9, and GO: ≥30). AO was defined as waist circumference was >102 cm in men, and >88 cm in women. Participants were asked about the number of falls in the previous year, and their clinical consequences. Logistic regression was used to estimate Odds Ratios (OR) and their 95% Confidence Intervals (CI). Models were mutually adjusted for GO and AO, and for the main confounders. We used the likelihood ratio test for interaction testing.
Results: During 1-year follow-up, 336 women suffered from falls, 168 required medical care, and 54 had fractures. In women, when comparing with those with normal weight, being overweight was positively associated with falling (OR 1.76; 95%CI 1.07-2.91), negatively associated with falls requiring medical care (OR 0.57; 95%CI 0.34–0.94), and with falls with fractures (OR 0.27; 95%CI 0.12–0.63). The corresponding results for GO were (OR 2.28; 95%CI 1.23–4.22), (OR 0.44; 95%CI 0.24–0.81), and (OR 0.30; 95%CI 0.11–0.82). On the contrary, suffering from AO was a negative predictor for suffering from falls (OR 0.55; 95%CI 0.34–0.89), and a positive predictor for falls requiring medical care (OR 1.82; 95%CI 1.12–2.94), and falls with fractures (OR 2.75; 95%CI 1.18–6.44). In men, results were similar to women but without reaching statistical significance (p for sex interaction=0.12).
Conclusion: In older women, GO is a risk factor for falling, and a protective predictor of falls requiring medical care. AO is negatively associate with falls, and positively associated with falls requiring medical care. BMI adjusted for WC may reflect lean mass, and hip adiposity may provide mechanical protection for adverse medical consequences of falls.



Funding Source: Data collection was funded by the following grants: FIS PI16/1512; PI16/1460; PI16/609; PI17/1709 (State Secretary of R+D and FEDER/FSE) Spanish Ministry of Economy and Competitiveness DEP2013-47786-R grant FEDER/FSE, the FRAILOMIC Initiative (EU FP7-HEALTH-2012-Proposal no. 305483-2), the ATHLOS project (EU H2020-Project ID: 635316), the SALAMANDER project (PCIN-2016-145), and the CIBERESP, Instituto de Salud Carlos III. Madrid, Spain.

CoAuthors: Helena Sandoval-Insausti – Hospital de la Princesa/UAM; Luz León-Muñoz – Universidad Autónoma de Madrid; Carolina Donat-Vargas – Universidad Autónoma de Madrid; Belen Moreno-Franco – IACS Aragón/Universidad de Zaragoza; Juan Gutierrrez-Fisac – Universidad Autónoma de Madrid; Fernando Rodriguez-Artalejo – Universidad Autónoma de Madrid; Ygor Hermenegildo – Universidad Autónoma de Madrid

Pilar G. Guallar Castillon (UAM Q2818013A)

Professor
Universidad Autónoma de Madrid Q2818013A./IMDEA-Food Institute. CEI UAM+CSIC, Madrid, Spain
Madrid, Madrid, Spain