Poster Topical Area: Energy and Macronutrient Metabolism

Location: Hall D

Poster Board Number: 453

P10-053 - Effect of Snack Type on Satiety in an Acute Feeding Study of Overweight and Obese Subjects

Monday, Jun 11
8:00 AM – 3:00 PM

Objectives: Snacking can be an important component of weight management, and snack choice is made based on a variety of factors such as macronutrient composition, satiety effects, and total calories per serving. In this study, we examined the effects on blood sugar and satiety in an isocaloric portion of two commonly consumed snacks: mixed nuts and pretzels. We hypothesized that mixed nuts would promote reduced hunger and beneficial metabolic responses which improve weight loss.

Methods: Subjects (N=54, age 29.7 ± 1.9 y, BMI 31.5 ± 0.6 kg/m2) came to the testing lab in the morning after an overnight fast, and an antecubital blood sample was take for baseline measures of glucose and appetite hormones. A baseline satiety questionnaire was also given. Subjects were then instructed to consume either the mixed nuts (42g) or pretzels (69g) along with 16oz of water in 15 minutes. Satiety responses were measured at 20, 40, 60, 90, and 120min, and a second blood sample was taken at 60min to measure blood glucose.

Results: Both mixed nuts and pretzels significantly increased measures of satiety (P<0.001) with greater satiety in pretzels compared to mixed nets (P<0.001). Pretzel consumption also showed a significant increase in postprandial blood glucose (P<0.001) compared to baseline, whereas nut consumption did not significantly increase postprandial blood glucose levels. Results also showed an inverse correlation of postprandial glucose and hunger feeling (coefficient -0.274, P=0.049), and a positive correlation with fullness (coefficient 0.441, P=0.001) at 60min after snack consumption.

Conclusions: A possible explanation for the increased satiety responses of pretzels over mixed nuts is the glucostatic theory which states that changes in arteriovenous glucose differences are detected by glucoreceptors that affect energy intake. Therefore, increases in blood glucose concentrations result in increased feelings of satiety and alternatively, a decrease in blood glucose has the opposite effect. It is unclear whether these increased feelings of satiety would reduce subsequent energy intake at the next meal, and this data warrants further investigation into how snacking effects weight management.

Funding Source:

American Heart Association (16GRNT31360007)

CoAuthors: Traci Roberts – San Diego State University; Natasha Godwin – San Diego State University; Shirin Hooshmand – San Diego State University; Mark Kern – San Diego State University

Mee Young Hong

San Diego State University
San Diego, California