Poster Topical Area: Aging and Chronic Disease

Location: Auditorium

Poster Board Number: 83

P01-064 - Early enteral nutrition improve the disease severity of severe acute pancreatitis: a retrospective study

Sunday, Jun 10
8:00 AM – 6:00 PM

Objectives: To investigate the effects of early enteral nutrition (EEN) in patients with severe acute pancreatitis (SAP) on the complication and disease severity.

Methods:
Sixty-six patients of severe acute pancreatitis were enrolled to this study and divided into two groups.Enteral nutrition was started within 48h after admission in the EEN group and from the 8th day in the delayed enteral nutrition (DEN) group.The disease severity markers were recorded,including blood amylase (AMS),serum albumin (ALB),C reactive protein (CRP),white blood cell count (WBC),and blood calcium level,etc.The incidence of infection and complications,abdominal pain relief time,hospitalization time,APACHE-II score were compared between the two groups after two weeks’ treatments.

Results:
No significant difference of APAHCE-II score between two groups was found before treatments(P > 0.05).The APAHCE-II score of the EEN group was higher than that of the DEN group after treatments and the difference was statistically significant(P<0.05).The severity markers and clinical outcome variables of the EEN group were significantly improved after treatments than that of the DEN group (P < 0.05).The abdominal pain relief time and hospitalization time were shorter in the EEN group than the DEN group, with statistical significant difference between the two groups (P < 0.05).The incidence of infection and complications of the EEN group was significantly lower than that of the DEN group (P < 0.05).
Conclusions:Early enteral nutrition support for patients with severe acute pancreatitis can improve disease severity and clinical outcome, shorten the hospitalization time. It is worthy of clinical use.


CoAuthors: GUOXUN CHEN, professor – Department of Nutrition, The University of Tennessee

Yipin Liu

Director,Professor
Department of Gastroenterology, Yantai Affiliated Hospital of Binzhou Medical University
Knoxville, Tennessee