Poster Topical Area: Obesity
Location: Hall D
Poster Board Number: 640
Objective: To compare the risk of developing cardiovascular diseases (CVD) in early-to-middle adults with normal weight (NW) and overweight/obese (OW) as well as to compare their dietary patterns.
Methods: Prospective and comparative study in which 53 subjects were recruited and categorized in 2 groups, NW (BMI25 kg/m2) of 28 and 25 subjects, respectively. Anthropometrics variables and blood pressure were evaluated. Three 24-hour dietary recall were obtained for each subject and a blood sample was obtained after 12 hours of fasting to evaluate lipid profile and glucose. Risk scores for predicting near-term incidence of hypertension and the 30-year CVD incidence from The Framingham Heart Study, were also calculated. Data was analyzed using STATA, 13.0 with a P < 0.05 considered as significant.
Results: There were no differences in age and height between groups. Weight, BMI, body fat and waist and hip circumferences were statistically higher in OW than NW subjects due to the study design. No differences were observed in total cholesterol, LDL-c and glucose but HDL-c (NW=54.8± vs OW=2431±856) was significantly higher in NW, while TAG (NW=69.2±31 vs OW=119.6±73) were significantly higher in OW group. Waist-hip ratio (NW=0.79±0.05 vs OW=0.88±0.1) and CT/HDL-c ratio (NW=3.2±0.9 vs OW=4.29±0.7) were higher in OW subjects but no differences were observed on LDL-c/HDL-c ratio. CVD risk score (NW=4.1±2.5 vs OW=10±7.8) and hypertension risk scores (NW=2.7±4.28 vs OW=9.3±8.9) were statistically different between groups. There were no differences in energy intake (NW=2610±866 vs OW=2431±856) and diet composition there were differences in carbohydrate (C) and fat (F) intake but there were not in protein (P) intake (C:48; F:36; P:16 vs C:52; F:32; P:16, in NW and OW, respectively) nor fiber, sodium and dietary cholesterol intake.
Conclusions: These results corroborate the susceptibility of OW subjects to develop CVD compared to NW subjects who has better CVD risk indicators, however, no differences in diet were identified that justify weight gain and the behavior of cardiovascular risk factors.
Francisco Humberto Castro-Sánchez
Universidad Autónoma de Sinaloa
Culiacán, Sinaloa, Mexico