Poster Topical Area: Obesity

Location: Hall D

Poster Board Number: 709

P23-082 - Anthropometric Indicators As Predictors Of Lipidic Changes In Brazilian Teens: The Loncaafs Study

Sunday, Jun 10
8:00 AM – 6:00 PM

Objectives. Identify the predictive power of the anthropometric indicators of overweight and obesity for lipidic alterations in adolescents. Methods. A cross-sectional study was conducted with 774 adolescents from both sexes (55% female), from 10 to 14 years old. The body mass index (BMI) by age was calculated by dividing the body weight by square height. For the calculation of the waist-to-height ratio (WHtR), we divided the waist circumference (WC) by height.The conicity index was computed considering body mass, height/stature and WC measurements.The changes in the lipid profile were defined according to one of the following conditions: high levels of total cholesterol (TC), high density lipoprotein (HDL), triglycerides (TG) and low levels of low density lipoprotein (LDL). The predictive power of the conicity index for changes in the lipid profile, as well as its cut-off points, was determined using Receiver Operating Characteristics (ROCs) curves. Results. For the altered LDL (ROC=0.69 [CI95%: 0.55-0.82]) and hypoalphaliproteinemia (ROC=0.68 [CI95%: 0.56-0.79]), BMI was the best predictor for male adolescents aged from 10 to 11 years old. For hypercholesterolemia in male adolescents from 10 to 11 years old (ROC = 0.61 [CI95%: 0.56-0.70]) and for hypoalphaliproteinemia in male adolescents from 12 to 14 years old (ROC=0.63 [CI95%: 0.56-0.70]), the WC was the best predictor. Regarding WHtR, it was the best predictor of hypercholesterolemia (ROC = 0.63 [CI95%: 0.55-0.70]) and hypoalphaliproteinemia (ROC = 0.64 [95% CI: 0.57-0.71] ) in adolescents in female adolescents aged 10 to 11 years and 12 to 14 years, respectively, and for hypertriglyceridemia in male adolescents 12 to 14 years old (ROC = 0.71 [95% CI: 59-0.82 ]). The conicity index was a good predictor for hypercholesterolemia (ROC = 0.63 [CI95%: 0.56-0.70]) and altered LDL (ROC = 0.65 [95% CI 0.55-0.75]) in male adolescents aged from 12 to 14 years, and in female adolescents from 10 to 11 years old (ROC = 0.70 [CI95%: 0.59-0.80] ) and from 12 to 14 years old (ROC = 0.62 [CI95%: 0.50-0.75]), for hypertriglyceridemia in male (ROC = 0.67 [CI95%: 0.50-0.85]) and female (ROC = 0.65 [CI95%: 0.50-0.79]) from 10 to 11 years old. Conclusions. The WHtR and the conicity index stand out from the other indicators and can be used as predictors of lipid abnormalities in adolescents.

Funding Source: São Paulo Research Foundation (FAPESP)
National Council for Scientific and Technological Development (CNPq)

CoAuthors: Dirce Marchioni, Researcher – Universidade São Paulo; Flávia Ferreira, Researcher – Federal University of Paraiba

Adélia C. Pereira

University São Paulo
São Paulo, Sao Paulo, Brazil