Poster Topical Area: Obesity
Location: Hall D
Poster Board Number: 649
Objectives: Research supports the use of Canadian diet and activity guidelines in family-centered lifestyle interventions (FCLI) to reduce adiposity while maintaining bone health in 6-8 y old children with obesity; however, it is unknown if this type of intervention will be successful in older children. This study aimed to assess changes in body composition and bone outcomes in 9-12 y old children with obesity participating in a 1-year family-centered lifestyle intervention.
Methods: Children were recruited from Greater Montréal (QC, Canada) and were randomized to participate in 6 interventions (FCLI) or control (Ctrl). Interventions were based on Canadian diet and activity guidelines. Anthropometric measures were used to calculate body mass index (BMI)-for-age-and-sex z-scores (BAZ), waist circumference (WC) was measured and whole body (WB) DXA (Hologic Discovery APEX software version 13:3.3) scans were analyzed at baseline and 12-mo for lean mass (LM), fat mass (FM) and percentage body fat (%BF). Bone outcomes included WB bone mineral content (BMC) and density (BMD). Data were analyzed using repeated-measures mixed model ANOVA with post-hoc adjustments, and were adjusted for season, mother's BMI, Tanner stage, and race.
Results: Children (n=60; mean age 11.1±1.1 y) were recruited; 55 completed the 12-mo visit. At baseline, the majority were Caucasian (80%) with mean BAZ of 2.7±0.2 and mean WB %BF of 38.2±4.4%. Compared to baseline, all groups significantly increased height (p<0.001) and LM (p<0.001) by 12-mo, however FCLI resulted in significant reduction of -0.1±0.1 in BAZ (p=0.003). Although BAZ did not change in Ctrl (0.0±0.1; p=1.00), at 12-mo Ctrl significantly increased WC by 4.0± 0.1 cm (p=0.01). Neither group significantly changed %BF by 12-mo, however, WB FM significantly increased in FCLI (0.2±0.7 kg; p<0.001) and in Ctrl (0.3±1.2 kg; p<0.001). Both groups significantly increased WB BMC (p<0.001) and WB BMD (p<0.001) at 12-mo compared to baseline; there were no differences between groups.
Conclusion: Children with obesity who participated in a 1-y family-centered lifestyle intervention that focused on Canadian dietary and activity guidelines resulted in modestly reduced BAZ while supporting bone health.
ClinicalTrials.gov: NCT01290016; H.W. is supported by Canada Foundation for Innovation, and Canada Research Chairs Program. T.C. is supported by Canadian Institutes for Health Research Doctoral Research Award.