Poster Topical Area: Dietary Bioactive Components
Location: Hall D
Poster Board Number: 268
Objectives: Investigate the effect of orange juice (OJ) along with a balanced diet on vascular endothelial function (VEF) and nutritional parameters in metabolic syndrome patients.
Methods: A randomized clinical study of parallel groups with short-term dietary intervention (48 ± 9 y). They were randomly assigned to the Control (n = 34) and OJ (n = 34) groups. All subjects received nutritional counseling for a balanced diet. In addition, the OJ group also received 500mL/day of 100% orange juice between meals (twice/day), while the Control group consumed snacks similar in calories to OJ (non-citrus fruits or pasteurized yogurt). All patients were followed for 12 wks, and anthropometric, dietary, biochemical, vascular endothelial function (VEF) parameters; and cardiovascular risk (Framingham Risk Score) were assessed.
Results: After 12 weeks of dietary intervention with or without OJ, significant reductions in body weight (-2%), BMI (-3%), fat mass (-6%), waist circumference (-5%) and visceral fat (-4%) were observed, without changes in lean mass. In the OJ group, significant reductions in glycemic (-4.5%), total cholesterol (-11.6%) and LDL-C (-17.2%) were detected. For both groups blood pressure decreased 8.5%, but only OJ group showed a decrease of -5% in the brachial artery diameter. The cardiovascular risk score indicated OJ decreased 15% the chance of cardiovascular event in the next 10 years, while the diet alone decreased 12%.
Conclusion: Orange juice, coupled with a balanced diet, improved the vascular profile, more than the balanced diet alone, for cardiovascular health. Both groups showed improvement in anthropometric characteristics and blood pressure.
Program for Scientific Development, Scholl of Pharmaceutical Sciences, UNESP (PADC/FCFAr), Coordination for the Improvement of Higher Education Personnel (CAPES-Brazil), Citrosuco S.A. and CitrusBR.
Sao Paulo State University - UNESP
Araraquara, Sao Paulo, Brazil