Poster Topical Area: Obesity

Location: Hall D

Poster Board Number: 722

P23-095 - Adiposity coassociates with insufficient vitamin D status at 1 month postpartum in healthy mothers from the Montreal region

Sunday, Jun 10
8:00 AM – 6:00 PM

Objective: To assess adiposity across lactation in healthy postpartum women with insufficient vitamin D status.


Methods:
Healthy mothers (n=93) who delivered healthy term babies at the Lakeshore General Hospital, Montreal, QC (Mar 2016 to Dec 2017) were studied within 1 mo postpartum (baseline), with repeated measures at 3 and 6 mo. Maternal ethnicity, family income, lifestyle and supplement use were surveyed. Obstetric history was collected from medical charts. Maternal blood was sampled only at baseline for measurement of total serum 25-hydroxyvitamin D (25(OH)D; Liaison, Diasorin Inc.). At each visit, weight and height were measured and body composition analyzed using dual-energy x-ray absorptiometry (DXA). Bioelectrical impedance analysis (BIA) was used to estimate total body water. Statistical analyses included mixed model ANOVA with repeated measures comparing mothers categorized using 25(OH)D concentration < (Insufficient) and ≥ (Sufficient) 50 nmol/L at baseline, with Tukey-Kramer post-hoc testing (p


Results:
Mothers were 31.8±4.6 y (average±SD). Postpartum, women with vitamin D insufficiency had a higher body-mass-index at baseline (Insufficient: 29.1±2.3 vs Sufficient: 26.0±2.1 kg/m2, p=0.006). Overall, from 1 to 6 mo the proportion of breastfeeding (97 to 85%) and supplements intake (74% to 58%) declined. At baseline, total body mass was lower in Sufficient mothers (Insufficient: 70.7±6.4 vs Sufficient: 58.8±6.4 kg, p=0.043) whereas by 6 mo postpartum Insufficient mothers had greater total (Insufficient: 35.4±2.1 vs Sufficient: 31.1±2.1 %, p=0.003), android (Insufficient: 35.5±2.7 vs Sufficient: 30.8±2.8 %, p=0.009) and gynoid (Insufficient: 40.3±1.5 vs Sufficient: 37.1±1.5 %, p=0.015) fat % (Figure 1). Total body water, android/gynoid and fat trunk/fat legs % ratio were not different between groups<./p>


Conclusions:
These data suggest that mothers with sufficient vitamin D status early in the postpartum period are leaner during the first 6 mo of lactation, whereas their counterparts have consistently higher body fat. Future research should investigate the impact of vitamin D supplementation in mothers at the beginning of lactation to help further understand these observations.



Funding Source: Canadian Institutes of Health Research
Canada Foundadtion for Innovation
Canada Research Chairs Program
Figure 1: Fat%, android and gynoid fat % in lactating women from 1 to 6 mo postpartum, n=93.

CoAuthors: Kristina Mullahoo, MSc – McGill University; Olusola Sotunde, PhD – McGill University; Shuqin Wei, PhD – University of Montreal; Catherine Vanstone, MSc – McGill University; Hope Weiler, PhD – McGill University

Nora Shero

PhD Student
McGill University
Pointe-claire, Quebec, Canada