Poster Topical Area: Dietary Bioactive Components

Location: Hall D

Poster Board Number: 355

P08-097 - Daily consumption of Aronia Melanocarpa (chokeberry) powders improves endothelial function in healthy individuals: a randomized controlled trial

Monday, Jun 11
8:00 AM – 3:00 PM

Objective: Aronia Melanocarpa is a rich source of polyphenolic compounds. Studies focusing on the cardiovascular health of berry (poly)phenols so far have been conducted with relatively high doses of fruit or juice that are impractical for daily consumption. This study aims to investigate the effect of low doses of Aronia powders on vascular function in young normotensive healthy males.


Methods:
A double-blind, parallel, controlled trial was conducted in 66 healthy male adults randomly allocated to a capsule of 500 mg of either Aronox® (Aronia extract standardized to 40% polyphenols), Aronia Full Spectrum (Aronia whole fruit powder), or placebo (artificially coloured maltodextrin). Each participant ingested one capsule every day for 12 weeks. Flow-mediated dilation (FMD), pulse wave velocity (PWV), augmentation index (AIx), blood pressure (BP), heart rate (HR) were assessed at baseline and 2 h on day 1 and 12 weeks later. Blood samples were taken at the same timepoints for serum biochemistry and (poly)phenol analysis.


Results:
Consumption of Aronox® and Aronia Full Spectrum for 12 weeks led to a significant increase in FMD compared with control (DFMD: 1.1±0.2 and 0.7±0.2 vs -0.1±0.2%, p=0.001 and p=0.044, respectively). Aronox® also significantly increased FMD 2 h post-consumption respect to control (DFMD: 1.5±0.2 vs 0.3±0.2 respectively, p=0.02). No statistically significant differences were found for other measurements.

Conclusions: In healthy young men, 12 week daily consumption of Aronox® and Aronia Full Spectrum improved endothelial function indicating that regular Aronia berry consumption has the potential to maintain cardiovascular health even in healthy individuals at low risk of cardiovascular disease.




Funding Source: Naturex

CoAuthors: Geoffrey Istas – King's College London ; Eleonor Wood – King's College London ; Claudia Rawlings – King's College London ; Jeeyoung Yoon – King's College London ; Vaishnavi Dandavate – King's College London ; Melanie Le Sayec – King's College London ; Emilie Fromentin – Naturex ; Ana Rodriguez-Mateos – King's College London

Ana Rodriguez-Mateos

Lecturer (Assistant Professor)
Kings College London
London, England, United Kingdom