Poster Topical Area: Global Nutrition

Location: Hall D

Poster Board Number: 570

P12-063 - Diet patterns and growth outcomes among HIV-exposed infants participating in the Kabeho Study in Kigali, Rwanda

Monday, Jun 11
8:00 AM – 3:00 PM

Objectives: Our goal was to identify nutrients consumed together in the common weaning diet of HIV-exposed and uninfected (HEU) infants in Kigali, Rwanda and to relate this dietary pattern to growth outcomes.

Methods: Single-day dietary recalls and anthropometrics were collected every 2–3 months from 581 infants followed from 6–24 months of age. Latent variables were constructed to reflect the population wide correlations in absolute intake (mg) or nutrient density (mg/100kcal) at 6-10 months, 11-15 months, 16-20 months, and 21-25 months. Values of the latent variables (diet scores) were calculated for each infant to reflect the extent to which the infant followed the diet observed in the general population. Regressions between the estimates of the latent variable and anthropometrics anthropometrics (length-for-age z-scores [LAZ] and weight-for-length z-scores [WLZ]) were conducted to determine the relationship between the identified common dietary pattern and growth outcomes.

Results: Mean absolute intake of zinc and calcium from complementary foods was insufficient for moderately breastfed infants. From 23–25 months, mean daily intake of zinc was 3.78 mg (recommended nutritn intake (RNI) 4.1mg) and calcium was 324mg (RNI 500mg). Infants tended to consume zinc, protein, calcium, and folate together across all periods. When measured by density, zinc, calcium, and retinol were consumed in combination. Infants with higher diet scores consumed cows milk and eggs more frequently and in larger amounts. Infants with low nutrient density diet scores were the most frequent consumers of grains, roots, and tubers. From 11-15 months, higher absolute intake diet scores were related to lower LAZ and higher WLZ. Similar results were seen for nutrient density scores from 6-15 months.

Conclusions: The common weaning diet in these HEU infants included a high intake of cows milk. This diet was related to poor growth outcomes: low LAZ and high WLZ. The traditional weaning diet replaced breast milk with cows milk too early, resulting in decreased linear growth but accelerated weight gain.

Funding Source: The Kabeho Study was funded by EGPAF through the United States Agency for International Development (USAID) Cooperative Agreement No. AID-OAA-A-12-00024. The data analysis was funded by MEASURE Evaluation through USAID Cooperative Agreement No. AID-OAA-L-14-00004. All authors have indicated they have no financial relationships relevant to this article to disclose.

CoAuthors: Gilles Ndayisaba – Elizabeth Glaser Pediatric AIDS Foundation ; Dieudonne Ndatimana – Elizabeth Glaser Pediatric AIDS Foundation ; Emily Bobrow – University of North Carolina at Chapel Hill, Elizabeth Glaser Pediatric AIDS Foundation ; Linda Adair – University of North Carolina at Chapel Hill

Charlotte Lane

Graduate Student
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina