Poster Topical Area: Obesity
Location: Hall D
Poster Board Number: 695
Objectives: To evaluate blood pressure levels and biochemical parameters of patients in the late postoperative (PO) of bariatric surgery.
Methods: An observational cross-sectional study, where adult individuals (18 to 60 years old) of both sexes were included, who underwent bariatric surgery, 2 to 7 years ago, by Roux en-Y gastric bypass. The percentage of excess weight loss (%EWL) was calculated in addition to the presence of weight regain (WR) of at least 10% in relation to the minimum PO weight. The systolic and diastolic blood pressures (SBP, DBP) were obtained through the average of 3 measurements. Prehypertension (PHT) was classified as SBP from 121 to 139mmHg and/or DBP from 81 to ≤89mmHg. Hypertension (HT) was identified when SBP≥140mmHg and/or DBP≥90mmHg. Glycemic alteration was defined as fast glucose ≥100mg/dL and insulin resistance if HOMA-IR>2.7. Renal function was evaluated by estimated glomerular filtration rate (eGFR) through the CKD-EPI equation and classified as normal when >90mL/min/1.73m². Dyslipidemia was defined as LDL-c≥160mg/dL and/or triglyceride ≥150mg/dL or HDL-c <40mg/dL for men and <50mg/dL for women. Chi-squared, Independent T-test or Mann-Whitney and Pearson's or Spearman's correlation were applied, as appropriate, to investigate association between health parameters and the presence of WR or %EWL.
Results: Twenty-one participants (38.8±6.2 years old; 85.7% women; 30.0±4.6 kg/m²) were enrolled in this analysis with a PO time of 4 years (2.6, 5.4). The %EWL was 72.6±17.8%, while 57.1% of the samples (n=12) presented WR, associated to significant higher levels of HOMA-IR (1.28±0.54 vs 1.01±0.47, p=0.04). The mean SBP was 116.4±11.8mmHg and DBP was 75.5±8.0mmHg, being classified with PHT 23.8% and HT 9.5% of the participants, with no significant difference between patients with or without WR. Biochemical profile was on average within the values. Negative associations between %EWL and basal insulin (r= -0.54, p=0.01) and HOMA-IR (r= -0.51, p=0.02) were observed.
Conclusions: Despite high frequency of WR, no higher HT was verified, and all biochemical markers were adequate, except for insulin resistance in WR group. A negative association was found between %EWL and insulin parameters.
Foundation for Research Support of the Federal District (FAPDF) – 0193.001.462/2016.
University of Brasília