Poster Topical Area: Maternal, Perinatal and Pediatric Nutrition
Location: Hall D
Poster Board Number: 406
To explore the effects of pre-pregnancy body mass index (BMI), gestational weight gain (GWG) and levels of maternal blood lipid, Vaspin, and Visfatin of on physical development of neonates in gestational diabetes mellitus.
Pre-pregnant body weight and gestational weight gain (GWG) were recorded in the subjects who delivered in a local hospital (96 Gestational diabetes mellitus and 131 control pregnancy women). Their blood samples were drawn for quantification of lipid profiles, Vaspin, and Visfatin. The physical measurement (weight, height, head circumference, and chest circumference) was recorded in the neonates. The association of maternal pre-pregnant BMI, GWG, and blood lipids, Vaspin, and Visfatin with the physical development of neonates was analyzed.
The birth weight and circumferences of chest and head in GDM group were larger than that in control group (Pmacrosomia (OR=2.307, 95%CI: 1.470~3.622); Pre-pregnant overweight/obese women had high risk to deliver macrosomia baby (OR=1.956, 95%CI: 1.145~3.342); The birth weight of neonates was lower in low GWG group than that in high GWG group (PP＞0.05).
GDM and Pre-pregnant overweight/obesity are the risk factor of having macrosomia, but they have no effect on neonatal body length and head circumference. Maternal lipid profile, serum Vaspin and Visfatin have no effect on neonatal birth weight, length, circumferences of head in GDM and non-GDM.
Key words: Gestational diabetes mellitus; Vaspin; Visfatin; Neonate
Zhengzhou, Henan, China (People's Republic)