Poster Topical Area: Vitamins and Minerals

Location: Hall D

Poster Board Number: 523

P26-062 - Association between serum vitamin B12 concentration and obesity in a nationally representative sample of US adults: NHANES 2011-2014

Sunday, Jun 10
8:00 AM – 6:00 PM

Objectives: Previous studies on the association of serum vitamin B12 concentrations with obesity have yielded inconsistent findings. We aimed to evaluate the associations of serum vitamin B12 concentrations with obesity in a nationally representative sample of US population.


Methods:
We included 9075 participants aged ≥ 20 years in the National Health and Nutrition Examination Survey 2011-2014. Serum vitamin B12 concentrations were measured by electrochemiluminescence immunoassay. It was also classified as normal levels (>221 pmol/L), insufficiency (148-221 pmol/L) and deficiency ((2. We used logistic regression with sample weights to estimate the odds ratios (ORs) and 95% confidence intervals (CIs).


Results:
Serum vitamin B12 concentrations were lower among obese adults compared with non-obese adults. After adjustment for age, gender, race/ethnicity, socioeconomic status, dietary and lifestyle factors, and use of medications that could affect the serum vitamin B12 levels, the multivariable-adjusted ORs (95% CIs) of obesity were 1.00 (reference), 0.93 (0.78, 1.12),0.82 (0.72, 0.94), and 0.66 (0.57, 0.77) (p for trend 221 pmol/L), insufficiency (148-221 pmol/L) and deficiency (


Conclusions:
In a large nationally representative sample of US adults, higher serum vitamin B12 levels were associated with lower risk of obesity.




Funding Source: N/A

CoAuthors: Minxian Sun – Wuhan Center Hospital; Buyun Liu – university of iowa; Yang Du – university of iowa; Shuang Rong – university of iowa; Linda Snetselaar – university of iowa; Wei Bao – university of iowa

Yangbo Sun

postdoc
university of iowa
Iowa City, Iowa