Poster Topical Area: Nutritional Epidemiology

Location: Hall D

Poster Board Number: 785

P20-081 - Excess fluoride in drinking water affects nutrition status in children

Monday, Jun 11
8:00 AM – 3:00 PM

Abstract: Fluorosis is a public health problem in 204 districts of India. Fluoride (F) ingestion affects nutrition status in children. Objective of the present study was to know the effect of excess F in drinking water on nutrition status of the children. For this purpose, a cross sectional study was undertaken in 1169 school going children of Nalgonda district, Telangana State, India. Villages were categorized into control (F=0.87mg/L, N= 645 from 4 villages) and affected (F=3.77mg/L, N=416 from 2 villages). Children were enrolled for dental grading screening for fluorosis by modified Dean Index criteria. Anthropometric measurements (height and weight) were used to assess nutritional status. Water and urinary F levels were analyzed by ion selective electrode method. Biochemical parameters like serum T3, T4, TSH, 25-OH vitamin D, and 1, 25-(OH)2 vitamin D were analyzed by radioimmunoassay kits. Results of the study revealed that the percentage prevalence of different grades of dental fluorosis was significantly higher in affected villages as compared to control villages. There was a significant increase in the urinary F in affected villages than control villages. Higher stunting was observed in affected village (26.3% in boys, 34.0% in girls) as compared to control village (24.5% in boys and 28.6% in girls). There was a significant decrease in serum T3 and 25-(OH) vitamin D levels in affected as compared control villages. Whereas there was a significant increase in serum T4, TSH, and 1, 25-(OH)2 vitamin D in affected than control villages. In conclusion excess fluoride in drinking water affects nutrition status along with vitamin D levels and thyroid function



Funding Source: UNICEF
Stunting Table and Dental Fluorosis image

CoAuthors: Vakdevi Validandi – ICMR National Institute of Nutrition

Arjun L. Khandare

Deputy Director (Sr. Grade), Scientist F
ICMR National Institute of Nutrition
Hyderabad, Telangana, India