Poster Topical Area: Global Nutrition

Location: Hall D

Poster Board Number: 558

P12-025 - Anemia and Birth Defects in Women of Reproductive Age in Southern India

Sunday, Jun 10
8:00 AM – 6:00 PM

Objectives: To establish a periconceptional surveillance system for anemia and birth defects prevention in Southern India.

Methods: This project has four stages: 1) census (completed), 2) biomarker survey (initiated), 3) birth defects surveillance (initiated), and 4) a randomized efficacy trial (planned). We conducted a census of all of the households within the catchment area (5-kilometer radius) of our community-based research site in Southern India. Trained nurses working as enumerators contacted households to obtain informed consent and collect sociodemographic data for all household members. Data collected from this census has been used to inform the random selection of women of reproductive age (15-40 y) for assessment of indicators of anemia and birth defects risk (e.g., iron, folate, vitamin B12 status). Women of reproductive age residing within households identified in the random sample are being contacted to determine current eligibility (i.e., 15-40 y, not pregnant or lactating) and invited to participate in the biomarker survey.

Results: During the census, 12,485 households have been contacted and 12,245 (98%) provided informed consent to participate (rural: n=5,748; urban: n=6,497). To date, a total of 10,894 women of reproductive age have been identified, including 449 (4.1%) pregnant, 1,357 (12.5%) lactating, and 9,178 (84.2%) non-pregnant and non-lactating women. Among women of reproductive age who are currently eligible (n=9,178), the median age is 28 years; 67.9% (n=6,229) are married, and 62.5% (n=5,736) have at least one child (median: 2). The sociodemographic characteristics of women of reproductive age were similar in urban and rural areas.

Conclusion: Findings will determine the burden of anemia, folate and vitamin B12 deficiency, and folate-sensitive neural tube defects risk in the region to inform the development of a randomized efficacy trial for anemia and birth defects prevention in Southern India.

Funding Source: Centers for Disease Control and Prevention

CoAuthors: Amy Fothergill, MPH – Cornell University; Christina Johnson, MS – Arogyavaram Medical Centre; Heather Guetterman – Cornell University; Beena Bose, MS – St. John's Research Institute; Yan Ping Qi, MPH – Centers for Disease Control and Prevention ; Wesley Bonam, MBBS – Arogyavaram Medical Centre; Anura Kurpad, MD, PhD – St. John's Research Institute; Krista Crider, PhD – Centers for Disease Control and Prevention

Julia L. Finkelstein

Assistant Professor of Epidemiology and Nutrition
Division of Nutritional Sciences, Cornell University
Ithaca, New York