Poster Topical Area: Aging and Chronic Disease

Location: Auditorium

Poster Board Number: 32

P01-011 - Associations of meat consumption with insulin resistance in African American adults without diabetes

Sunday, Jun 10
8:00 AM – 6:00 PM

Objectives: We examined associations between red and processed meat intake and insulin resistance and the possible influence of overall dietary quality on these associations.

The Jackson Heart Study is a prospective cohort of adult African Americans. Of the 5,306 participants enrolled at baseline (2000-04), 3,819 attended visit 3 (2009-13). Of these participants, those with baseline diabetes (n=770) and missing data on baseline diet, baseline and visit 3 insulin resistance, and potential confounders (n=970) were excluded. Our final sample size was n=2,097 (53±12 y, 64% female). Diet was assessed using a validated semi-quantitative food frequency questionnaire. Meat intake was extracted from mixed dishes. Unprocessed beef was categorized as beef; unprocessed pork as pork; cured pork, cold cuts, and sausage as processed meat; and unprocessed beef and pork as red meat. Total meat included beef, pork, and processed meat. Participants were categorized by tertile of meat consumption (ounces/day). Baseline and follow-up (visit 3) insulin resistance levels were estimated using the homeostasis model assessment of insulin resistance (HOMA-IR), which is based on fasting glucose and insulin levels. Dietary quality was characterized using the Healthy Eating Index 2015 (HEI) score modified to exclude contributions from meat.

Baseline intakes of total meat, beef, and pork were not significantly associated with HOMA-IR at follow-up, adjusted for baseline HOMA-IR (Table 1). Consistent results were observed for red meat (data not shown). All results remained similar after adjustment for HEI score (Model 3). Greater processed meat intake was associated with a small increase in HOMA-IR values (Tertile 1 vs. 3, 2.25 vs. 2.48, P-trend = 0.009, Model 4). We did not observe any evidence that baseline HEI score modified the associations of total meat, beef, pork, and processed meat consumption with HOMA-IR at follow-up (P-interaction >0.1 for all models).

We observed a small positive association between processed meat, but not red meat, consumption and HOMA-IR at follow-up. These preliminary data suggest that moderation of processed meat intake could be a beneficial part of lifestyle modification approaches to manage insulin resistance among African American adults without diabetes.

Funding Source:

National Cattlemen's Beef Association, a contractor to the Beef Checkoff

Table 1

CoAuthors: Sabrina Noel – University of Massachusetts Lowell; Sameera Talegawkar – George Washington University; Teresa Carithers – University of Mississippi ; Adolfo Correa – University of Mississippi Medical Center; Katherine Tucker – University of Massachusetts Lowell

Sherman J. Bigornia

Assistant Professor
University of New Hampshire
Durham, New Hampshire