Poster Topical Area: Aging and Chronic Disease

Location: Auditorium

Poster Board Number: 16

E15-01 - Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in adults with obesity

Sunday, Jun 10
8:00 AM – 6:00 PM

Objective: Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in subjects with obesity has never been examined.This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in adults with obesity.

Methods:
Subjects with obesity (n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group (n = 23).
Results:
Body weight and energy intake decreased in the time restricted group (-2.6% ± 0.5; -341 ± 53 kcal/d) relative to controls over 12 weeks (P < 0.05). Systolic blood pressure decreased in the time restricted feeding group (-7 ± 2 mm Hg) versus controls (P < 0.05). Fat mass, triglycerides, fasting insulin, insulin resistance, and homocysteine decreased over time with time restricted feeding (P < 0.05 for main effect of time, no group x time interaction). LDL cholesterol, HDL cholesterol, fasting glucose, lean mass, and visceral fat mass were not significantly different form the control group after 12 weeks (no group x time interaction).

Conclusions:
These findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss, without calorie counting. It may also offer clinical benefits by reducing blood pressure.





Funding Source: University of Illinois Chicago Campus Research Board Pilot Grant; National Institutes of Health (NHLBI) R01HL106228 and (NIDDK) (F32DK107157).

CoAuthors: Krista Varady, PhD – University of Illinois at Chicago

Kelsey Gabel

Graduate Student
University of Illinois at Chicago
Chicago, Illinois