Poster Topical Area: Nutritional Epidemiology
Location: Hall D
Poster Board Number: 805
Objective: The purpose of this study was to review previously published meta-analyses on the effectiveness of dietary fiber on reducing the incidence of cancer.
Methods: An umbrella review of all published meta-analyses was performed. A PubMed search from January 1, 1980 to October 30, 2017 was conducted using the following search strategy: (fiber OR fibre) AND (meta-analysis OR systematic review) AND (cancer OR carcinoma). Only English language publications that provided quantitative statistical analysis on cancer were retrieved.
Results: Nineteen meta-analyses comparing highest versus lowest dietary fiber intake were retrieved for inclusion in this umbrella review. There was a statistically significant reduction in the relative risk (RR) of colorectal, esophageal, gastric and pancreatic cancer (RR=0.52-0.88), however statistically significant heterogeneity was observed in the meta-analyses on esophageal, gastric and pancreatic cancer. There was a statistically significant reduction in the relative risk of breast cancer (RR=0.85-0.93).
Conclusion: This review suggests that those consuming the highest amounts of dietary fiber may benefit from a reduction in the incidence of developing colorectal cancer and there also appears to be a small reduction in the incidence of breast cancer.
National University of Health Sciences