Poster Topical Area: Nutritional Epidemiology
Location: Hall D
Poster Board Number: 803
Objective: The purpose of this study was to review previously published meta-analyses on the effectiveness of dietary fiber on cardiovascular disease.
Methods: An umbrella review of all published meta-analyses was performed. A PubMed search from January 1, 1980 to October 30, 2017 was conducted using the following search strategy: (fiber OR glucan OR psyllium OR fructans) AND (meta-analysis OR systematic review). Only English language publications that provided quantitative statistical analysis on cardiovascular disease, lipid concentrations or blood pressure were retrieved.
Results: Thirty-one meta-analyses were retrieved for inclusion in this umbrella review, and all meta-analyses comparing highest versus lowest dietary fiber intake reported statistically significant reductions in the relative risk (RR) of cardiovascular disease mortality (RR=0.77-0.83), as well as the incidences of cardiovascular disease (RR=0.72-0.91), coronary heart disease (RR=0.76-0.93) and stroke (RR=0.83-0.93). Meta-analyses on supplementation studies using β-glucan or psyllium fibers also observed statistically significant reductions in both total serum and LDL cholesterol concentrations.
Conclusion: This review suggests that individuals consuming the highest amounts of dietary fiber intake can significantly reduce their incidence and mortality from cardiovascular disease. Mechanistically these beneficial effects may be due to dietary fibers actions on reducing total serum and LDL cholesterol concentrations between 9.3-14.7 mg/dl and 10.8-13.5 mg/dl respectively.
National University of Health Sciences