Introduction & Objective : In the treatment of urethral strictures, urethroplasty has been demonstrated to be an effective, durable, and cost-effective surgical option. Limited investigation exists to understand whether obesity is an independent risk factor for urethroplasty failure. We sought to assess whether BMI is an independent predictor for stricture recurrence following urethroplasty.
Methods : We performed a retrospective review of patients undergoing urethroplasty between 2007 and 2014, identifying 137 patients for study inclusion. Data collected included body mass index (BMI), patient demographics, and surgical characteristics including age, stricture length and location, etiology, and urethroplasty technique. Logistic regression was performed to assess predictors for stricture recurrence using both univariate and multivariate models.
Results : Mean patient age and follow-up was 47 years (±16.4) and 92 months (±30.5), respectively. A recurrence rate of 17% was identified, with a mean time to recurrence of 29 months. There was no difference when comparing the mean BMI in patients with and without recurrence (28.9 vs 30.4 kg/m2, respectively)(p=0.40). A higher rate of stricture recurrence was seen when comparing the cohort with a BMI < 25 versus remaining cohorts (BMI 25-30; BMI >30). However, in univariate and multivariate analysis, BMI failed to demonstrate statistical significance as a predictor for urethroplasty outcome (Table 1). On multivariate analysis, fasciocutaneous repair type was predictive of stricture recurrence. No additional potential predictors assessed were found to be significant.
Conclusions : In the present study, BMI did not independently predict stricture recurrence following urethroplasty.