Concurrent Session 3B: The Current and Future State of Personalized Medicine: Hype or Hope?; CME (AMA PRA Category 1 CreditsTM) 1.5; CEU (NSGC category 1) 0.15; Attendance CEU 1.5

Thursday, September 13
10:15 AM - 11:45 AM
Location: Mayo Civic Center Rooms 104-105

The goal of this session is to present the audience with a brief history of the incredible revolution in DNA sequencing capabilities, to describe what is the current state of state-of-the-art sequencing, and then to envision where we’ll be in five years. We will discuss pros and cons of taking next generation sequencing capabilities into the clinic, real success stories, and the  greater hype around the current power of these technologies and a number of instances where way too much was claimed than could be substantiated about using some genomic information to make informed clinical decisions.

Learning Objectives:

Concurrent Speaker :
Konstantinos Lazaridis, MD

Professor of Medicine, College of Medicine and Science
Center for Individualized Medicine
Mayo Clinic
Rochester, Minnesota

Konstantinos Lazaridis, MD is considered a leader in the area of the genomics of chronic cholestatic liver diseases, namely, Primary Biliary Cirrhosis (PBC) and Primary Sclerosing Cholangitis (PSC). Since 2003, he has established and is the principal investigator of the two national consortia for studying patients afflicted with these diseases. His research group applies the latest genomic and genetic epidemiology approaches to better understand the pathogenesis and improve the therapy of patients with PBC and PSC. This research effort is supported by the NIH. He was elected to the American Society of Clinical Investigation (ASCI) in 2015.

As associate director of the Center for Individualized Medicine in Rochester, Dr. Lazaridis has been instrumental in establishing and expanding the Individualized Medicine Clinic and in directing the Clinomics program that seeks to integrate the latest genomic discoveries into clinical care. Dr. Lazaridis is a physician in the Division of Gastroenterology and Hepatology and the Everett J. and Jane M. Hauck Associate Director, Center for Individualized Medicine, Mayo Clinic in Rochester. Dr. Lazaridis received his medical degree at the University of Ioannina in Greece. He completed his Internal Medicine and Gastroenterology fellowship training at Mayo Clinic and was a Mayo Clinic Scholar in Genomics in the laboratory of Dr. Francis Collins at the National Human Genome Research Institute.

Presentation(s):

Send Email for Konstantinos Lazaridis

Concurrent Speaker :
Linnea Baudhuin, PhD

Associate Professor of Laboratory Medicine and Pathology, College of Medicine and Science
Center for Individualized Medicine
Mayo Clinic
Rochester, Minnesota

Linnea M. Baudhuin, PhD is Associate Professor of Laboratory Medicine and Pathology at the Mayo Clinic in Rochester, MN, USA. Dr. Baudhuin is co-director of the Personalized Genomics Laboratory and the Clinical Genome Sequencing Laboratory at Mayo Clinic. Dr. Baudhuin received her PhD in Clinical Chemistry from Cleveland State University in conjunction with the Cleveland Clinic. She then completed fellowships in Clinical Chemistry and Clinical Molecular Genetics at Mayo Clinic. She is board certified in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics. Dr. Baudhuin’s clinical and research interests are related to Personalized Medicine and lie primarily in the areas of cardiovascular-related inherited disorders, pharmacogenomics, and next-generation sequencing.

Presentation(s):

Send Email for Linnea Baudhuin

Concurrent Speaker :
Michael Joyner, MD

Professor of Anesthesiology, College of Medicine and Science
Anesthesiology
Mayo Clinic
Rochester

Michael J. Joyner, MD focuses his research on cardiovascular control in conscious humans and he is especially interested in the interaction between local vasodilator signals, sympathetic vasoconstriction and the regulation of arterial pressure. More recently his team has developed an interest in the idea that the carotid chemoreceptors can sense blood glucose and evoke counter-regulatory responses to hypoglycemia. Over the years he has used a variety of physiological models and pharmacological tools to study these topics in humans during small and large muscle mass exercise, mental stress, body heating, hypoxia and orthostatic challenge. Dr. Joyner’s lab has been continuously funded by the NIH since the early 1990s. Dr. Joyner is a recognized expert on athletic performance and the physiology or world records. He has also had major editorial duties with the Journal of Physiology London and Journal of Applied Physiology and has participated in numerous peer-review panels for various funding agencies in the U.S. and abroad including serving as a charter member on two NIH study sections and chair of the CICS panel.

Dr. Joyner is the Frank R. and Shari Caywood Professor of Anesthesiology at Mayo Clinic where he served as deputy director and associate dean for Research from 2005-2010. He was named a Distinguished Investigator by his colleagues at Mayo in 2010 and has given numerous named lectureships throughout the world. He received his undergraduate and medical degrees from the University of Arizona in Tucson, Arizona and obtained residency and research training at the Mayo Clinic.

Presentation(s):

Send Email for Michael Joyner

Concurrent Speaker :
David I. Smith, PhD

Professor of Laboratory Medicine and Pathology
Mayo Clinic
Rochester, Minnesota

David I. Smith, PhD is a Professor in the Department of Laboratory Medicine and Pathology. He is also the Chairman of the Technology Assessment Group for the Mayo Clinic Center for Individualized Medicine. His laboratory works on two main projects. The first is the characterization of the common fragile sites, which are regions of profound genomic instability that are found in all individuals. The second project is to study the different roles that human papillomavirus plays in the development of different cancers. His group uses next generation sequencing and other advanced genomic technologies to address these two projects.

Presentation(s):

Send Email for David Smith


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Concurrent Session 3B: The Current and Future State of Personalized Medicine: Hype or Hope?; CME (AMA PRA Category 1 CreditsTM) 1.5; CEU (NSGC category 1) 0.15; Attendance CEU 1.5

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