Innovation Showcase

Innovation Showcase Thursday lunchtime



Dr. Anne Bang will discuss the use of hiPSC-derived neurons, including iCell® GABANeurons and iCell DopaNeurons, in high-throughput assays for phenotypic analyses and drug screening. She will describe the development of a suite of foundational assays in higher throughput formats to monitor neuronal morphology, mitochondrial function, and electrophysiology, and address the challenges of balancing higher throughput with relevance. Dr. Cedric Bardy will discuss patch-seq characterization of hiPSC-derived neurons with electrophysiology, morphological analysis and single-cell RNAseq. The integration of single-cell electrophysiology, morphology and transcriptomics analysis of live human neural cells enables a bridging of human neurophysiology with gene expression. This novel approach allows the identification of neurons in specific functional states and can compensate for variations among cell lines.

Innovation Showcase: CDI

6/21/2018
11:30 - 12:30

Presented by: CDI 

Presentations:

Send Email for Anne Bang

Send Email for Cedric Bardy


Assets

Innovation Showcase: NOVEL APPLICATIONS OF HUMAN IPSC-DERIVED NEURONS: FROM HIGH-THROUGHPUT SCREENING TO PATCH-SEQ ANALYSIS - CDI



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Send Email for Innovation Showcase: NOVEL APPLICATIONS OF HUMAN IPSC-DERIVED NEURONS: FROM HIGH-THROUGHPUT SCREENING TO PATCH-SEQ ANALYSIS - CDI