Innovation Showcase

Innovation Showcase Friday lunchtime



Cell therapy for Parkinson’s disease (PD) based on pluripotent stem cell (PSC) derived products is approaching clinical trials. Malin Parmar will give an update on latest developments on her road to the clinic aiming at the first in man study for PD in Europe using ES derived dopaminergic progenitors. This will include GMP manufacturing and cryopreservation of the cells, as well as a discussion of the key pre-clinical in vivo assays for safety and efficacy. Sebastian Knöbel will highlight recent developments towards an automated manufacturing platform for ATMPs, the CliniMACS Prodigy. A closed system Tubing Set and software package adapted for adherent cells together with high quality QC and cell culture reagents constitute major advances for development and scaling of cell manufacturing processes for a variety of applications. Besides PSCs expansion and DA differentiation, MSC isolation from bone marrow plus subsequent cultivation will be presented. Finally, cells sorting using the GMP compliant cell sorter MACSQuant Tyto will be discussed in the context of ATMPs.

Innovation Showcase: Miltenyi

6/22/2018
11:30 - 12:30

Presented by: Miltenyi Biotec 

Presentations:

Malin Parmar

Lund University, Sweden

Malin Parmar is a professor in cellular neuroscience at Lund University. Together with her lab she has shown in a series of high profile publications how human fibroblasts can be converted into neurons, how glial cells can be reprogrammed into neurons in vivo, and how functional dopamine neurons can be generated from human embryonic stem cells. She is the recipient of an ERC starting grant and an ERC Consolidator grant as well as a VR Consolidator Grant. In 2016 she was awarded a New York Stem Cell Foundation – Robertson investigator award.
Her research has a strong translational focus and she collaborates with Industry partners to develop new, stem cell based therapies for Parkinson’s Disease.

Presentation(s):

Send Email for Malin Parmar

Sebastian Knoebel

Miltenyi Biotec GmbH, Nordrhein-Westfalen, Germany

Presentation(s):

Send Email for Sebastian Knoebel


Assets

Innovation Showcase: TOWARDS A THERAPY FOR PARKINSON’S DISEASE: LATEST RESEARCH HIGHLIGHTS AND CONCEPTS FOR MANUFACTURING OF ATMPS - Miltenyi



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Send Email for Innovation Showcase: TOWARDS A THERAPY FOR PARKINSON’S DISEASE: LATEST RESEARCH HIGHLIGHTS AND CONCEPTS FOR MANUFACTURING OF ATMPS - Miltenyi