Wageningen University and Research, Netherlands
Ben Scheres has defined anatomically, experimentally and genetically the root stem cell organization in Arabidopsis, a model system he has developed as appropriate for multidisciplinary dissection of developmental mechanisms. His group was the first to show that the stem cell niche concept was applicable to the plant kingdom. He identified transcription factors defining a dose-dependent combinatorial stem cell identity specification mechanism and has shown that the Retinoblastoma pathway controls stem cell differentiation– allowing comparisons of stem cell maintenance mechanisms across plant and animal kingdom. The group is strongly engaged in computational modeling and mathematical analysis of pattern formation mechanisms.
13:25 – 13:50