Leonard I. Zon

Boston Children's Hospital, MA, United States

Dr. Zon is the Grousbeck Professor of Pediatric Medicine at Harvard Medical School, an Investigator at Howard Hughes Medical Institute, and the Director of the Stem Cell Program at Boston Children’s Hospital. He is internationally-recognized for his pioneering work in stem cell biology and cancer genetics, and has been the preeminent figure in establishing zebrafish as an invaluable genetic model for the study of the blood and hematopoietic development.

Presentation(s):

• 1 - TOPIC OVERVIEW BY CHAIR

  6/22/2018
  13:15 – 13:20

• 5 - THE START OF CANCER - STEM CELL CHANGES, CLONAL EXPANSION AND NICHE REGULATION

  6/23/2018
  10:40 – 11:05

Andrew George Elefanty

Murdoch Childrens Research Institute, VIC, Australia

Andrew Elefanty MB BS FRACP PhD. Goup leader, Blood Cell Differentiation and Disease laboratory, Murdoch Childrens Research Institute, Melbourne.

Andrew Elefanty trained as a physician and completed a PhD in leukaemogenesis at the Walter and Eliza Hall Institute of Medical Research. He studied globin gene regulation at the National Institute for Medical Research in London before returning to the Hall Institute to pursue interests in developmental haematopoiesis and mouse embryonic stem cell differentiation. He moved to Monash University to initiate studies with human embryonic stem cells. His laboratory relocated to the Murdoch Childrens Research Institute to continue work focused on pluripotent stem cell differentiation to haematopoietic lineages. His laboratory aims to model blood diseases and generate cells for transplantation.

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Elizabeth Ng

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Freya F. Bruveris

Murdoch Children's Research Institute / Melbourne Univerity, Victoria, Australia

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Monica Nafria I Fedi

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Ana Rita Leitoguinho

Murdoch Childrens Research Institute, Victoria, Australia

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Ali Motazdian

Murdoch Children's Research Institute, Victoria, Australia

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Jasna Kusur

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Penny McDonald

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Tanya Labonne

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Edouard Stanley

Presentation(s):

• 2 - MODELING NORMAL AND MALIGNANT HAEMATOPOIESIS USING HUMAN PLURIPOTENT STEM CELLS

  6/22/2018
  13:20 – 13:45

Vanessa Lundin

Boston Children’s Hospital and Dana-Farber Cancer Institute, MA, United States

Presentation(s):

• 3 - YAP REGULATES HEMATOPOIETIC STEM CELL FORMATION IN RESPONSE TO THE BIOPHYSICAL FORCES OF BLOOD FLOW

  6/22/2018
  13:45 – 14:00

Lei Ding

Columbia University Medical Center, NY, United States

Presentation(s):

• 4 - LIVER-DERIVED SYSTEMIC THROMBOPOIETIN IS REQUIRED FOR BONE MARROW HEMATOPOIETIC STEM CELL MAINTENANCE

  6/22/2018
  14:00 – 14:15

Kathryn S. Potts

Albert Einstein College of Medicine, NY, United States

Presentation(s):

• 5 - THE SPLICEOSOMAL COMPONENT SF3B1 IS ESSENTIAL FOR ZEBRAFISH HEMATOPOIETIC STEM CELL FORMATION THROUGH REGULATION OF THE JAK/STAT SIGNALING PATHWAY

  6/22/2018
  14:15 – 14:30

Luena Papa

Mount Sinai, NY, United States

Presentation(s):

• 6 - ROS SUPRESSION THROUGH P53 ACTIVITY AND A REMODELED MITOCHONDRIAL NETWORK DETERMINES THE FATE OF FUNCTIONAL HUMAN HEMATOPOETIC STEM CELLS DURING EX-VIVO EXPANSION

  6/22/2018
  14:30 – 14:45

Stephen Ting

Monash University, VIC, Australia

Presentation(s):

• 7 - CONSTITUTIVE DELETION OF AP2A2 RESULTS IN FETAL LIVER HAEMATOPOEISIS EXHAUSTION DUE TO LOSS OF HSC QUIESCENCE AND PERTURBED ASYMMETRICAL:SYMMETRICAL HSC FATE

  6/22/2018
  14:45 – 15:00