National Institute for Basic Biology, Japan
Shosei Yoshida studies mouse spermatogenesis at National Institute for Basic Biology (NIBB), Okazaki, Japan, as a professor of Division of Germ Cell Biology since 2008. With a background of developmental and cell biology, Shosei is interested in dynamical aspects of stem cells in the mouse testis, with regard to their fate behaviors (viz. proliferation, differentiation and death), localization and motion. His group developed an intravital live-imaging strategy, combined with fate analysis of pulse-labeled cells and mathematical analysis (collaboration with Ben Simons of Cambridge). Shosei discovered active stem cell migration near vasculature and reversible potential of differentiation-destined cells to return to the stem cell pool, relevant to the breakdown of intercellular bridges between spermatogonia that had been believed to be a perdurable structure.
13:20 – 13:45