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T.7 - A novel role of human lung endothelial cells in allergic airway disease by producing and responding to IL-33

T.22 - A role for early oral exposure to house dust mite proteases in food allergy susceptibility

F.115 - Airway epithelium from asthmatic patients have altered immune responses to human rhinovirus infection

F.99 - Duration of attenuation of allergic responses after modulation of idiotypic regulatory network

W.89 - Elevated Local and Systemic Allergen-specific IgA Following Timothy Grass Sublingual Immunotherapy

F.53 - IL-10 producing lung resident memory TR1-like cells do not protect against allergic airway inflammation

W.40 - Local Immunoglobulin E Production in Colorectal Polyps of Patients with Food Allergy

T.20 - NHERF1 mediates the pathogenesis of airway inflammation in a murine model of house dust mite-induced asthma

F.35 - Physicochemical Characterization of Philippine Grass Flora for Diagnosis of Respiratory Allergies

W.113 - Progressive increase in allergen concentration abrogates immune tolerance in ovalbumin-induced murine model of chronic asthma

T.21 - The Effect of Fenretinide on Regulatory B Cell Development and Semaphorin 4C in Allergic Asthma Model

T.57 - A molecular characterization of meningeal inflammatory infiltrates in the progressive multiple sclerosis brain

T.6 - A novel self-regulatory mechanism of Th17 cells controls autoimmune uveitis through interleukin-24

W.69 - Abatacept Selectively Modulates CD4+ Treg, Tfh, and CD38-expressing T cells in the Periphery of Patients with Relapsing-Remitting Multiple Sclerosis

F.88 - Acute and Chronic Damage by Autoantibodies in a Model of Neuropsychiatric Systemic Lupus Erythematosus

T.81 - Cbl-b deficiency in the myeloid cell lineages but not T cells is responsible heightened Th17 response

W.9 - Detection and Characterization of Novel Myelin-reactive CD8+ T cell Populations in Multiple Sclerosis

F.56 - Dysregulation of peripheral lymphocytes in Myalgic encephalomyelitis/Chronic Fatigue Syndrome

W.46 - Exosomal let-7i inhibits the differentiation of regulatory T cells in multiple sclerosis

T.97 - Fingolimod Modulates T Cell Phenotype and Regulatory T Cell Plasticity in vivo

F.19 - From T Cell Receptor to antigen, systems approach to discovering T cell antigen(s) in Multiple sclerosis and Experimental autoimmune encephalomyelitis

W.110 - Immunoglobulin A is a critical regulator of demyelinating neuroinflammation

T.16 - Immunological Dysregulation in Neuromyelitis Optica and its Recovery Following Anti-IL-6 Receptor Monoclonal Antibody Tocilizumab Treatment

F.17 - Increases in Eomes-expressing Th cells in secondary progressive multiple sclerosis reveal patients at risk of increased disability

F.94 - Induction of Self-Tolerance in Chronic Experimental Autoimmune Encephalomyelitis Using Mixed Chimerism and Allogeneic Neural Stem Cell Transplantation

W.73 - iNKT cell ligand OCH induces anti-inflammatory immune responses in patients with multiple sclerosis: Results of investigator-initiated, first-in-human phase 1 study

W.54 - Mass Cytometry assisted phenotyping identified structural rewiring of immune system in refractory epilepsy

F.75 - Myelin-Specific CD8+ T cells Recruited to the Central Nervous System During CD4+ T Cell-Induced Autoimmunity Exacerbate Brain but not Spinal Cord Disease

W.82 - Ocrelizumab does not modulate peripheral T cell functionality or prevalence in a small subset of relapsing MS patients enrolled in OPERA I, a phase III double-blind doubledummy interferon beta-1a-controlled study

F.29 - Recirculating Intestinal IgA-producing cells Regulate Neuroinflammation during EAE in mice

T.31 - Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment

W.4 - Subsets of micro-RNAs may serve as novel biomarkers and therapeutic targets in multiple sclerosis

W.5 - The expression signature of very long non-coding RNA in myalgic encephalomyelitis / chronic fatigue syndrome

T.67 - TIGIT Regulates CD4 Autoreactive T cells in Multiple Sclerosis

F.119 - TOLERance Induction with Autologous Tolerogenic Dendritic Cells Treated with VITamin D3 and Loaded with Myelin Peptides in Multiple Sclerosis (TOLERVIT-MS trial): The Design of a Multicenter, Dose-Escalation Phase I Clinical Trial

T.40 - A Natural Killer cell based disease activity score for Rheumatoid arthritis patients: Novel mathematical intervention in rheumatic disease biology

W.60 - A Novel “Anti-Vaccine” for the Treatment of Collagen-Induced Arthritis

F.78 - A protective langerhans cell-keratinocyte axis is dysfunctional in lupus photosensitivity

W.105 - Autoantibody profile and clinical significance in Idiopathic Inflammatory Myositis

F.100 - BAFF promotes progressive lupus nephritis via activation of the B cell surface receptor TACI.

F.58 - Characterization of a novel epigenetic regulator required for T helper 17 differentiation

F.38 - Computational Analysis of Clinical Data in a Well-Phenotyped Lupus Cohort Points to Disease Subtypes

F.74 - Dermal lymphatic function and photosensitivity in a lupus model

T.29 - Development of citrullinated-vimentin-specific CAR for targeting Tregs to treat autoimmune rheumatoid arthritis

T.44 - Dysregulation of Innate, Adaptive and TNF-Superfamily Immune Pathways Alongside Autoantibody Accrual Informs a Biological Surrogate for Clinical Disease Activity in Lupus

T.61 - Elevated Neopterin Levels are Associated with Dyslipidemia in Juvenile Dermatomyositis

T.87 - Enhancers in Autoimmune Disease Cells Contribute to Disease Pathogenesis

W.47 - Enrichment of RORγt+ Innate-like T Cells in Intestinal Biopsies from Spondyloarthritis Patients

W.93 - Evaluation of the LIA-ANA-Profile-17S for the detection of autoantibodies to nuclear antigens

F.52 - Extracellular vesicles in systemic juvenile idiopathic arthritis

W.20 - Gene Expression Analysis Delineates the Roles of Multiple Type 1 Interferons in Systemic Lupus Erythematosus

F.43 - Gene Expression Analysis Reveals Different Ancestry Related Cellular Contributions to Systemic Lupus Erythematosus (SLE)

T.37 - High dimensional analysis of immunome in systemic sclerosis reveals abnormalities in frequency and function of MAIT cells

W.31 - Identification of a novel B cell subset in Systemic Lupus Erythematosus using AMNIS Imaging Flow Cytometry

F.89 - Immune Cells Avoid Death from Immunoproteasome Inhibitors by Switching to Conventional Proteasome

T.46 - Immune Cells From Sisters Of Lupus Patients Highlight Important Pre-disease Epigenetic States And The Factors That Induce Them

F.44 - Integration of BCR, TLR, BAFF Receptor and TACI Signals Promotes Autoantibody Production by Transitional B Cells in BAFF Transgenic Mice

T.68 - Integrative Analysis of Clinical and Molecular Data on a Well-Phenotyped Lupus Cohort Identifies Molecular Associations with Disease Manifestations

W.55 - Kidney Infiltrating T cells in Murine Lupus Nephritis are Metabolically and Functionally Exhausted

W.48 - Low density granulocytes and Neutrophil Extracellular Traps as key players of disease activity in patients with idiopathic inflammatory myopathies

W.75 - Manipulation of Immune Checkpoints via an Epitope-Specific Vaccine Restores Immune Tolerance and Induces Clinical Amelioration in Human Rheumatoid Arthritis.

T.35 - MicroRNAs as novel biomarkers of disease development and therapeutic response in autoimmune arthritis

T.54 - Molecular mechanisms of autophagic memory in pathogenic T cells in human arthritis.

F.5 - Multi-cohort transcriptome analysis implicates novel biological mechanisms in active systemic lupus erythematosus

F.16 - New Insights in the Pathogenesis of Immune-Mediated Necrotizing Myopathies: Role of Auto-Antibodies and Complement in vitro and in vivo

W.42 - Novel innate and adaptive immunity abnormalities as key risk factors for infections in patients with systemic lupus erythematosus: Results from the GERMEN cohort

W.52 - Pathological Consequences of Anti-PAD4 Antibody Binding to the Surface of Monocytes: Implications in Rheumatoid Arthritis

F.7 - Persistence of Transcriptomic Signature in CD4 Memory T Cells in Polyarticular JIA Patients despite Anti-TNFA Biologics Therapy

T.48 - Prolactin and autophagy in Systemic Lupus Erythematosus: Clinical significance of correlation between PRL-Receptor and Atg14+ expression on B and T reg Cells.

F.28 - Selective inhibition of NF-kB inducing kinase (NIK) is therapeutically efficacious in IFN-accelerated lupus nephritis prone mice

T.86 - Specialization of Vascular Adventitial Fibroblasts Correlates with Lymphocyte Infiltration in Human Dermal Diseases

T.73 - The SLE-associated Gene BANK1 Inhibits Macroautophagy and Restricts Plasma Cell Differentiation and Immunoglobulin Production by Human B Cells

F.65 - The transcriptional co-activator BOB.1 inhibits plasma cell differentiation and induces costimulatory capacity of B cells in GC-like environment

W.111 - Using metabolomics to understand the immunopathogenesis of juvenile-onset SLE and stratify patient groups

T.69 - Vitamin D reduces the Th17-phenotype in ACT1/Act1-associated Systemic Lupus Erythematosus

W.85 - Autologous iPSC-derived Thymic Epithelial Cells as Cell Therapy to Restore Thymic Function in Stem Cell Transplant Recipients

W.90 - Biomaterial Substrate-Mediated Three-Dimensional Culture Enhance the Immunosuppressive Action of Mesenchymal Stem Cells on Inflamed Immune Cells In Vitro and In Vivo

W.32 - Expression of Programmed cell death protein-1 (PD-1) on T cells after Allogeneic Hematopoietic Stem Cell Transplantation

F.107 - Fate of Endothelial progenitor cells in an altered intracellular and mitochondrial calcium homeostasis

T.114 - Impact of HLA disparity in the UCB transplant outcome of malignant and non-malignant diseases

F.3 - iR-HLA cassette: An automated and integrated solution for NGS based HLA-typing

F.11 - MicroRNA-23a Plays an Essential Role in Graft-versus-Host Disease

T.47 - Scatterbodies for Morphometric Profiling by Single Cell Mass Cytometry in Human Hematopoietic Cells

W.115 - TIM-1 in the donor graft modulates graft-versus-host disease following allogeneic hematopoietic cell transplantation

W.109 - An aberrant SPDEF-CCL2 molecular mechanism promotes metastasis of prostate cancer

F.117 - Epigenetic editing of FOXP3 in human T cells induces overexpression and is sufficient to create a regulatory T cell phenotype in vitro.

T.70 - ILC2s and Type 2 Immunity Influences Hair Follicle Stem Cell Proliferation and Skin Homeostasis

W.27 - Investigating the expression, function and regulation of IL-17A and IL-17F expressing CD4+ T cells in human health and inflammatory disease

F.62 - Is Depression a Consequence of Immunological Changes among Heavy Users of Alcohol?

F.69 - Progression from NAFLD to NASH: Miscommunication between the intestinal microbiota and the CD4 T-cells as a potential cause

T.118 - Quantitative Bead-Based Multiplex Immunoassays for Human Bone Metabolism

W.100 - Targeting IL-17-producing T cells attenuates the severity of Pseudomonas aeruginosa lung infection

T.13 - Toxoplasma gondii Induces IL-1β Production and Pyroptosis Independent Release from Primary Human Monocytes through the Syk Signaling Pathway

F.47 - A Novel Mendelian Model of Autoimmune Diabetes

T.19 - A Single Dose of Siltuximab can Transiently Modify T-effector Resistance to Suppression in T1D

F.2 - Aire-dependent thymic FoxP3+ regulatory T cells in Type 1 Diabetes

T.79 - Autologous Activation of Diabetogenic CD3+ T Cells in an In Vitro Model of Type 1 Diabetes

F.63 - Circulating CXCR5-PD1hi Peripheral T Helper Cells are Increased in Children with T1D and in Autoantibody-Positive Children At-risk for T1D

T.49 - Combined Features of T and B Cells Define Distinct Immunotypes of Adult T1D Subjects

T.30 - Discovery of a novel human anti-IL-2 antibody that potentiates Regulatory T cells by a structure-based mechanism

F.67 - Follicular regulatory T cells expand in the peripheral blood of patients with type 1 diabetes and express reduced levels of PD-1 in the pancreatic lymph nodes

W.1 - Glucokinase is Recognized as an Autoantigen in Subjects with Type 1 Diabetes

W.2 - HLA-dependent association of systemic antibody responses to intestinal commensal bacteria with islet autoimmunity in pediatric cohorts

F.54 - Hyaluronan Levels are Increased in Serum and Muscle of Human Subjects with Type 2 but not Type 1 Diabetes Independently of Glycemic Control

F.84 - Hypo-responsiveness is the dominant phenotype of memory T cells following Alefacept treatment of new onset T1D.

T.28 - Immune Checkpoint Inhibitor Diabetes Mellitus: An Atypical Presentation of Type 1 Diabetes Mellitus?

W.8 - Islet Antigen-Specific CD8 T Cells Within Individual Type 1 Diabetes Subjects Exhibit Multiple Distinct Phenotypes Which Include Features of Both Early Differentiation and Exhaustion

F.71 - KLRG1+TIGIT+ CD8 T Cells are a Hyporesponsive Cell Type Varying in Quantity across Individuals and Disease Conditions

F.114 - Major impact of 'aging' of adaptive immunity on high-fat diet-induced insulin resistance and nonalcoholic steatohepatitis

T.83 - Modulation of cytokine production by dietary fatty acids in T cells from Type 1 Diabetes-susceptible NOD mice

W.37 - PD-1 and PD-L1 expression in Graves’ disease’s thyroid glands. A clue to better understand the pathogenesis and immune checkpoint immunotherapy-associated thyroid autoimmunity

F.34 - Peripheral Blood Gene Expression Profiling to Identify Biomarkers of Disease Susceptibility in Type 1 Diabetes

T.77 - Pro-inflammatory tissue-resident fibroblastic reticular cells promote destructive immune responses in type 1 diabetes.

F.113 - Reversal of autoimmune diabetes and restoration of self-tolerance via a cell-based therapy in NOD mouse model

W.6 - Single-cell RNAseq Identifies Expanded Clones and Specific Characteristics of Islet Antigen-Reactive Memory T Cells in Peripheral Blood of T1D

W.83 - Sustained Delivery of IL-2 Using an Injectable Hydrogel Prevents Autoimmune Diabetes

W.41 - Targeting Chronic Inflammation in Ageing and in Type 2 Diabetes Patients using Metformin

W.16 - The leader region of preproinsulin contains common epitopes for islet-infiltrating CD8 T-cells derived from organ donors with type 1 diabetes

W.87 - Brugia malayi recombinant Cystatin ameliorates development of murine Colitis by induction of IL-10+ T-regulatory cells and IL-10+ B1-cells

F.81 - Characterization of extra-thymic AIRE-expressing cells using single-cell RNA sequencing

F.57 - Different cell types contribute to unique components of the interferon signature in SLE PBMCs

F.92 - Dissecting human regulatory T cell signaling using chimeric antigen receptors

W.35 - Dynamic Functional Phenotypes of B- and T helper-cells from Autoantibody-positive First Degree Relatives Mark Distinct Stages of Type I Diabetes (T1D) Progression

W.107 - Editing of effector T cell activation pathways to model Teff resistance

F.26 - Elucidating the Function of Mosaic, a Novel Gene Mediating Autoimmunity

T.75 - Foxp3 Domain-Swap Interface is Required to Suppress T Helper Type 2 Transcriptional Program in Regulatory T cells

W.62 - Genetically Engineered Tolerogenic Dendritic Cells for Antigen-specific Immunotherapy

W.49 - How pro-inflammatory markers and molecular mediators may contibute to immune failure and autoimmunity in aging

T.39 - Immunological characterization of IgA Nephropathy patients

W.61 - Low-dose Interleukin-2 Expands and Increase Responsiveness of Circulating Regulatory T Cells in Patients with Autoimmune Hepatitis

T.82 - Mice Lacking αvβ6- and αvβ8-integrin Activity Display Impaired Thymic Epithelial Cell Maturation

W.38 - Modeling the thymic selection of human autoreactive T cells in vivo

W.67 - Regulatory Dendritic Cell-Based Strategies for the Development of Innovative Therapies for Celiac Disease

F.79 - Regulatory T cells mediate the selection of peripheral naïve B cells

T.64 - Role of native mouse thymus and lymphopenia-driven expansion in the development of an autoimmune-like syndrome in humanized mice

W.11 - Serum Antibody Specificities in Healthy Infants Reveals a Significant Autoreactive Profile

T.59 - Simplified protocol for enrichment of primed human Th17 and Tc17 lymphocytes from peripheral blood.

T.90 - The IL-6 receptor alpha chain is essential for the biological function of IL-6

F.61 - The role of thymic tolerance in the pathogenesis of the COPA syndrome

W.19 - Understanding Immune System Sex Differences in the Healthy Human Transcriptome

W.39 - VISTA.COMP is an engineered checkpoint receptor agonist that suppresses T-cell mediated immune responses.

W.21 - Exploration of SCAMP5 as a Novel Lupus Risk Gene

F.1 - Gene editing in primary human T cells to assess autoimmune associated SNPs within the gene PTPN22

W.17 - Gene Expression Profile of Tolerogenic Dendritic Cells Differentiated with Vitamin D3, Dexamethasone and Rapamycin

T.52 - Human Sinonasal Immunoglobulin D Gene Mutations and Clonal Compartmentalization

W.23 - Impact of genetic polymorphisms on human immune cell gene expression

W.71 - iReceptor: A Platform for Querying and Analyzing Antibody/B-cell and T-cell Receptor Repertoire Data across Federated Repositories

T.116 - PBMC Fixation and Processing for Chromium Single-Cell RNA Sequencing

F.45 - RASGRP3 Intronic Variants Affect its Expression, and a Possible Mechanism That Might Contribute to Lupus Risk

W.74 - A new, positive control peptide pool with broad infectious antigen and MHC coverage that may be useful for assessing anti-infectious T-cell responsiveness

T.115 - All-in-One, Quantitative Immune Repertoire Profiling from Challenging Samples

T.100 - Analysis of Infiltrating B Cell Populations in the Tumor Microenvironment Using Single Cell Transcriptomics

T.94 - Anti-TNF Therapy in Spondyloarthritis: Prediction of Therapeutic Responses Using Immunological Signatures

W.12 - Deep Immunology Model Learns Healthy Patient Status from Cytometry Fingerprint

F.37 - Development of 12+ color modular staining panels with a common backbone to interrogate CD40L-based activation of human B cells, PBMC, neutrophils and monocyte-derived dendritic cells

T.33 - Differential expression CD16 epitopes recognized by clones 3G8 and B73.1 on resting and activated Natural Killer cells.

W.65 - Dried Cells as Controls or Standards

F.118 - Flow cytometry: identifying biomarkers for the diagnosis of organ-specific autoimmune diseases and response to treatment

W.70 - High prevalence of S. pyogenes Cas9-specific T cell sensitization within the adult human population – A balanced effector/regulatory T cell response

T.99 - Immune Monitoring of CD34+ Stem Cell Derived Natural Killer Cell Therapy (PNK-007) In A Phase I Study of Acute Myeloid Leukemia

F.33 - MHC class II Dextramers - A new tool for detection of antigen specific CD4+ T-cells

T.41 - Peripheral lymphocyte subpopulations at onset of type 1 diabetes: imbalance of naïve and memory T cells

W.3 - Robust prediction of clinical outcomes using cytometry data

F.60 - The CD43-Mediated Signals Differentially Regulate CD4 And CD8 T Lymphocytes Function

W.92 - TotalSeq™ , Standardized oligonucleotide barcode antibody conjugates, and Veri-Cells™ PBMC for multiplex immunophenotyping by single cell sequencing

F.39 - Using Indocyanine Green Dye to Image Immune Cells in the Human Retina during Ocular Disease

W.66 - Absence of Sprouty 1 and 2 Enhances CD8+ T Cell Memory Development and Function

F.85 - Adjuvant treatment with a dialyzable leukocytes extract contributes to maintain HPV-infected women free of low-grade cervical lesions.

T.109 - Akt-2 Is a Potential Therapeutic Target for Disseminated Candidiasis

F.91 - Antibodies secretion promoted by a recombinant BCG strain induces a protective immune response against human respiratory viruses

F.77 - CD161 Promotes Prenatal Immune Suppression of Human IFNgamma-producing PLZF+ T Cells

F.106 - CD8 T cell memory frequency and repertoires to influenza and Epstein Barr virus co-evolve with increasing age from young adult to elderly

T.110 - Differential signaling through TLR7 or TLR8 determines the phenotype of human monocytes during RNA viral infection.

W.104 - Early Cytokine Signatures Discriminate Persistent from Resolving MRSA Bacteremia

F.105 - Effect of 17β-estradiol, Progesterone and Prolactin on the Infective Capacity of Toxoplasma gondii, Cytokine Modulation and the Expression of Hormonal Receptors on THP-1 Cells

F.103 - Epigenetic and Transcriptomic Signatures Associated with Antibiotic-Persistent MRSA Bacteremia

W.99 - Estrogen Receptor Alpha (ERα) Antagonist Mediates Therapeutic Benefit against Urinary Tract Infection (UTI) by Boosting TNFα Production in Bladder

T.34 - Extended Phenotypic Immunome Characterization (EPIC): A Reference Atlas of the Changing Immune Landscape from Birth to Adulthood

W.101 - Fcγ-Receptor Binding and Fc-Mediated Antibody Effector Functions in a Human HIV-1 Vaccine Efficacy Trial

T.111 - HECT E3 Ubiquitin ligase Nedd4 is required for anti-fungal innate immune response

F.30 - Human Memory CD8 T cell Effector Potential is Epigenetically Preserved During In Vivo Homeostasis

W.97 - Human Tonsil Cultures as a Model to Study Adaptive Immune Responses In Vitro

F.102 - IL-10 production by myeloid cells is essential to keep the lung integrity during infections caused by the major pathogenic bacteria Klebsiella pneumoniae ST258 and Streptococcus pneumoniae.

F.49 - Immune Paralysis and Lymphopenia is Associated with Adenosine A1 Receptor Dysfunction

W.102 - Immune Response to Influenza Vaccine in Sickle Cell Disease Patients

F.20 - Influenza A virus (IAV) infection in humans leads to expansion of highly diverse CD8 T cell repertoires cross-reactive with Epstein Barr virus (EBV)

W.103 - Lymphatic Filariasis Infection is reemerging in India emphasizing the need for a Prophylactic Vaccine for mass control

W.94 - Macrophages Contribute to Protective Memory in Recurrent Staphylococcus aureus Skin and Invasive Infection

T.89 - Mechanosensitivity of Immature Dendritic Cells in Mechanically Tunable Three-Dimensional Matrices

W.77 - Molecular mechanisms underlying in vitro-rejuvenation of virus-specific memory T cells

F.70 - Molecular profiling of human regulatory T cell subsets supports a linear differentiation model and identifies a novel regulatory T cell population with stem cell-like properties

W.91 - Novel adjuvant systems elicit unique and protective cellular and humoral immune responses in Q fever challenge model using a polyvalent C. burnetii vaccine

W.53 - Nutrient sensing by CD11c+ cells modulates host microbiome to promote metabolic homeostasis

W.106 - Pharmacological Induction of Heme Oxygenase-1 Hinders Herpes Simplex Virus Replication by Interfering With The Nuclear Accumulation of Viral Capsids after Infection

T.63 - Phase I clinical trial for a recombinant BCG expressing the nucleoprotein of the human respiratory syncytial virus (hRSV) in healthy adults.

F.80 - Pioneering bacteria in fetal meconium drive divergent intestinal T cell development

W.114 - Respiratory Syncytial Virus Glycoproteins Activate Primary Human Dendritic Cells

W.96 - Riding The Perfect Storm. Severe Rash Resulting From Simultaneous Infection with Influenza B virus, Erythrovirus B19 And Influenza B immunization

F.18 - Role of CD1d receptor in the pathology caused by the human Respiratory Syncytial Virus and the human Metapneumovirus

T.45 - Seroprevalence of Brucella-specific antibodies in at-risk subjects among rural and suburban communities in different provinces of southern regions of Saudi Arabia

T.84 - Serum Level of Soluble Programmed Death Protein-1 as a Predictor of Disease Progression in Patients with Nontuberculous Mycobacterial Lung Disease

W.28 - Signal Integration in Immune Regulatory Networks

W.112 - Soluble protein biomarkers in late-onset neonatal sepsis: potential value in diagnosis

F.82 - Strategy for performing second treponemal tests in reverse-sequence algorithms of syphilis diagnosis

W.15 - Th17/regulatory T cells balance is predictive of Coccidioides infection outcome in pediatric patients

T.55 - The long chain fatty acid transporter, MFSD2A, is essential for memory CD8+ T cell formation and maintenance

W.45 - The NLRP3 inflammasome impairs CD8+ T cell responses in murine viral hepatitis.

F.13 - Transcriptional Signatures of Influenza Vaccine Immune Responses in Elderly Individuals

T.80 - Tyrosine Phosphorylation of NLRP3 by Src Family Protein Tyrosine Kinase Lyn Suppresses NLRP3 Inflammasome Activation

F.22 - A combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency

W.18 - A novel Btk mutation manifesting as late-onset x-linked agammaglobulinemia

T.53 - Aberrant Innate-Like Lymphocytes Causing Atopy and Immune Dysregulation in a Patient With a Novel BCL11B Variant Revealed by Mass Cytometry (CyTOF)

F.68 - Antibody Profiling Identifies a Strong and Wide Spread Auto-Immune Response in Idiopathic CD4 Lymphopenic Patients

F.36 - Flow Cytometry as a Screening Tool of Primary Immunodeficiency Diseases

F.97 - Importance of individual titration and monitoring in vitro of ruxolitinib treatment of patients with STAT1 GOF mutations

T.58 - Lentiviral-mediated FOXP3 gene transfer to convert CD4+ T cells to Treg cells: a suitable method for immunotherapy

F.104 - Mechanisms of Thymic Hypoplasia in Mouse Models of 22q11.2-DiGeorge Syndrome

T.91 - Patients with Novel Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Have a Severe Immunodeficiency without Alopecia or Nail Dystrophy

F.83 - Role of Rho kinases in B cell development

W.25 - The mechanisms of immune system dysregulation in Common Variable Immunodeficiency – the role of T helper cells

F.46 - The Thymus in the Chromosome 22q11.2 Deletion Syndrome (22q11DS)

F.12 - Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes

T.43 - Using Transcriptional Profiling to Understand Early Human T Cell Development

W.57 - Assessing a potential role of stem cell memory T cells as cancer-initiating cells in Sézary syndrome

F.76 - IgA Nephropathy presenting with Chronic Urticaria

F.14 - Immunomodulation and regeneration effect of biosynthetic dressing loaded with silver nanoparticles and TNFa inhibitor in a non-traumatic wounds experimental model

F.41 - MIF gene polymorphisms are not a genetic risk factor for NSV susceptibility in a Western Mexican population

F.48 - Multidimensional Approaches to Define the Risk and Immunopathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Associated with Nevirapine in South Africa

T.3 - SEB stimulation induces functional pathogenic features in Th17 cells from psoriasis patients

T.15 - Tc17/MAIT cells in Psoriatic Arthritis: Regulatory role of the IL-23 and its receptor system

T.71 - Unexpected cutaneous effects in IL31-deficient animals

T.10 - A New Model of Autoimmune Retinopathy Demonstrates the Critical Importance of IL-10 to Retinal Protection

T.4 - An abnormal mucosal immune response to an ocular surface commensal precipitates inflammation in a model of Muckle-Wells Syndrome

T.56 - Association Study between HLA genes and Climatic Droplet Keratopathy (CDK) in a cohort from the Patagonian region of Argentina

W.24 - Clinical effect of IRT5 probiotics on dry eyes

F.55 - Macrophage Activity and Survival are Regulated by Exosomes from Retinal Pigment Epithelial Cells

T.65 - The induction of specific systemic tolerance to encephalitogenic antigens via the ocular route or adoptive transfer of cells

W.88 - Therapeutic recovery of retinal pigment epithelial cell suppression of macrophage phagocytic activity by alpha-melanocyte stimulating hormone is not through the melanocortin 5 receptor

F.86 - Activation of Endogenous Anergic Self-specific CD8+ T cells by Polymeric Nanoparticles for Enhanced Cancer Immunotherapy

F.4 - Augmentation of a Novel Adenoviral Vaccine Strategy By Checkpoint Inhibitors

F.8 - Boosting anti-tumor response by conferring cysteine autonomy to T cells

F.109 - Chemotherapy Potentiates Immunotherapeutic Efficacy of Recombinant Oncolytic Poliovirus

W.81 - Control of lymphocytic leukemia through regulation of TRAF1 protein degradation

F.6 - ConvertibleCAR T-Cells Provide Dose Control of Activity and Targeting Flexibility

T.93 - Discovery screen platform for co-modulators of T cell effector function against tumors

T.74 - Dissecting The Cellular Mechanisms Of Disease Pathology Caused By Gain-Of-Function Mutations In PIK3CD

F.21 - Engineering Antigen-Specific T cells from Human Pluripotent Stem Cells

T.62 - Epigenetic Reprogramming of Intratumoral Regulatory T cells Enhances Cancer Immunity

W.14 - ESCAPE RNA sequencing: combining protein and nucleic acid measurements to profile immune cells

T.38 - ESCAPE TCR sequencing: Combining TCR sequencing with protein based cellular phenotyping in immune profiling

T.117 - Forcing melanoma cells to be stressed stimulates apoptotic and immunogenic responses

T.98 - Genetic Modification Potentiates the Anti-Tumor Activity of Human Cord Blood Progenitor (CD34+) Derived NK Cells

T.105 - Improved T Cell Activation Bioassays to Advance the Development of Bispecific Antibodies and Engineered T Cell Immunotherapies

W.72 - In vitro generated Tr1 cells eliminate primary pediatric acute myeloid leukemia

T.5 - Induction of T-allo10, an alloantigen specific Type 1 regulatory T cell product suitable for cellular therapy in hematopoietic stem cell transplantation for hematologic malignancies

T.104 - Measurement of Fc-mediated ADCC and CDC Activity of anti-TNFα and anti-VEGF Therapeutic Antibodies using Reporter-based Bioassays and Engineered TNFα+ and VEGF+ Target Cells

W.58 - Mutations of forkhead box P3 and their impact on hepatocellular carcinoma

W.79 - NLRP3 inflammasome promotes IL-17-mediated tumor immunity while increasing IDO1 in the tumor microenvironment.

F.95 - PD-1 blockade markedly enhances immunity to prostate tumors by adoptively transferred human Vγ2Vδ2 T cells in an NSG mouse model

T.106 - Quantitative Cell-Based Bioassays to Advance Immunotherapy Programs Targeting Immune Checkpoint Receptors

T.107 - Reproducible MOA-Reflecting Reporter-Based Bioassays to Enable Drug Development of Biosimilars and Biobetters

T.92 - Reprogramming human T cell function and TCR specificity with non-viral genome targeting

T.26 - Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.

W.108 - Single-cell Highly Multiplexed Proteomics Identifies Novel Polyfunctional Human CD8+ T-cell Signatures Induced by a Nanoparticle-Based Melanoma Vaccine in Human Immune System Mice

F.108 - Single-cell Polyfunctionality of CD4+ T-cells Shows Promise as a Predictor of Overall Survival of Pancreatic Cancer Patients Treated with GVAX Vaccine

T.95 - Skewed CD4 and CD8 T cell differentiation in pancreatic cancer patients

W.64 - The interaction of ILT3/LILRB4 receptor with its ligand CD166/ALCAM inhibits tumor cell growth

F.96 - Tmem176b is a checkpoint in IL-1β-dependent tumor immunity

W.76 - Tumor-resident memory CD8+ T cells are exhausted and less cytotoxic despite epigenetically committed in bladder cancer

F.23 - Using Synthetic Biotic™ Medicines to Activate Innate and Adaptive Immunity and Drive Antitumor Immune Response

T.36 - A Novel Whole Blood Assay Detects Flagellin-Specific CD4+ T Cells in Patients with Inflammatory Bowel Disease

T.25 - Alpha Kinase 1 Controls Intestinal Inflammation via Suppression of the IL-12/IL-23 Axis

W.56 - Analysis of Cecal Immune Response in a Murine Model of Colitis Using Intravital Imaging

F.111 - Anti-TNFα Therapy increases Suppressor Regulatory T Cells in patients with Crohn’s Disease

F.73 - Building an Immune Single Cell Atlas of Ileum Crohn’s Disease

W.78 - Effect of concurrent systemic glucocorticoid use on CSF T lymphocytes in Patients with Moderate-to-Severe Crohn’s Disease

F.64 - Effects of Short-term Dietary Changes on Immune System and Beyond

T.78 - Mesenchymal Stem Cells have attenuated differentiation and clonogenic potential in Ulcerative Colitis

F.112 - Metabolic inhibition of microbiota-reactive CD4 T cells for the prevention and treatment of inflammatory bowel diseases

F.50 - Mice Overexpressing MKL1 in Macrophages Are Susceptible to DSS-induced Colitis

W.84 - Therapeutic potential of Wuchereria bancrofti derived Macrophage Migration Inhibitory Factor-2 (rWba-MIF-2) in DSS induced colitis mouse model

W.33 - Adhesion and degranulation promoting adaptor protein regulates both direct and indirect anti-tumor responses of invariant natural killer T cells

F.15 - An atlas of the mosquito immune system at single-cell resolution

F.31 - Caspase-1 Laden Extracellular Vesicles from Cystic Fibrosis Lungs Activate Inflammasome Signalling in Neutrophils and Epithelial Cells

F.101 - Diminished B cell response after repeated influenza vaccination

W.116 - Glutathione peroxidase 8 negatively regulates caspase-4/11 to protect against colitis by restraining NLRP3-inflammasome activation

W.63 - High throughput screening of IRAK4 small molecule inhibitors in TLR ligand stimulated whole blood

T.76 - HMGB1 Redox Forms Differentially Mediate Innate-to-Adaptive Immune Switch after Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation

T.103 - IL-5 signaling in structural or hematopoietic cells protects mice against acute lung injury

T.2 - Immune-modulatory role of miR-511-3p on Mannose Receptor Expression and impact on Human DC Function

W.29 - Implications of silver nanoparticles on phenotypic changes in murine bone-marrow derived dendritic cells

W.43 - Inflammatory phenotypes of monocytes/macrophages in acute CPP arthritis: a comparison with acute gouty arthritis

W.98 - Innate Lymphoid Cells are Activated in Acute Dengue Infection and Persist through Clinical Resolution

T.60 - Mass Cytometry-Based Analysis of Human Lung Macrophages

T.108 - Mycobacterium leprae proteins, GroES and MMP-II, induce extracelullar traps in human neutrophils

W.13 - Neutrophils shed tethers that form a new class of elongated shear-derived particles (SDP)

F.66 - Opposing roles of CD2 and 2B4 in iNKT cell cytotoxic responses

F.51 - Posttranscriptional Control of Microglia-derived Neurotrophic Factors

T.27 - Protective Roles of Myeloid SOCS3 to Neuroinflammation in Neurodegenerative Parkinson’s Disease

T.9 - Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses

W.22 - STING Associated Vasculopathy with onset in Infancy (SAVI) and Chronic Atypical Neutrophilic Dermatosis with Lipodystrophy and Elevated Temperature (CANDLE) are autoinflammatory diseases driven by active type I interferons

T.85 - The induction mechanism of Interferon regulatory factor 5 in HMGB1-induced macrophage polarization

F.27 - Unique effects of human Tr1 cells on suppressing innate immunity and promoting epithelial health

T.14 - B cell immune repertoire sequencing identifies pre-transplant rejection risk

T.17 - dentification of Transplant Injury Specific Metabolites in the Kidney Transplant Urine By Metabolomics

T.72 - Endothelial expression of MHC Class I is necessary for transfusion-related acute lung injury

W.44 - Identification of leukocyte subpopulations as potential biomarkers of long-term survival with normal allograft function after lung transplantation

F.72 - Phenotypic and Clonal Analysis of Recipient B cells and Plasma Cells Repopulating Graft Mucosa Reveals an Association with Rejection after Human Intestinal Transplantation

F.59 - Profile of human alloreactive T cells stimulated by CD40L-stimulated B cells and monocyte-derived dendritic cells

T.66 - The preferential expression of donor-HLA molecules by ‘cross-dressed’ cells following clinical liver transplantation is mediated be extracellular vesicles

W.34 - Tr1 cell immunotherapy promotes transplant tolerance via de novo Tr1 cell induction and is safe and effective during acute viral infection

T.88 - Fatty Acid Binding Protein 5 is required for Treg metabolism and function

W.59 - Activation and expansion of CD8+ T cells in cord blood and in the maternal-fetal interphase during preterm labor.

W.26 - AIRE Supports Maternal-Fetal Tolerance During Early Pregnancy

T.12 - Helios drives preferential regulatory T cell differentiation in fetal naïve T cells

F.40 - IgA antiphospholipid antibodies: exploring their role in the diagnosis of Antiphospholipid Syndrome in recurrent reproductive failure patients.

W.51 - Integrative analysis of miRNA and mRNA sequencing in spontaneous preterm birth

T.24 - Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth

W.7 - Peripheral Blood Cell MicroRNA predicts Preeclampsia and Preterm Birth when collected Early in the First Trimester of Pregnancy

T.42 - Prevalence of Antiphospholipid Antibodies among Groups of Reproductive Failure. Association with Natural Killer Cells and Another Immunological Alterations.

T.18 - A novel inhibitor (N5-1) of interferon regulatory factor 5 (IRF5) ameliorates disease severity in NZB/W F1 mice

F.93 - A Synthetic Biology Approach for the Treatment of Cancer and Inflammation

W.86 - Addition of anti-CD2 to anti-CD3/CD28-conjugated nanoparticles increases expansion of human CD4+ T cells and IL-10-transduced CD4+ type 1 regulatory T cells

T.112 - Antibody-Mediated Protection from an Adenovirus-Vectored RSV Vaccine

W.68 - Antisense Spherical Nucleic Acids Targeting IL-1β for Inflammatory Diseases

T.51 - Building CRISPR/Cas9-based platforms for therapeutic target identification and validation

T.101 - Depletion of Membrane LTα Expressing Cells in Combination with TNFα Neutralization Provides Superior Efficacy in Rheumatoid Arthritis Preclinical Model

F.90 - Development of new hollow mesoporous silica nanoparticles coated with mAb Trastuzumab to treat breast carcinoma

T.11 - Direct control of inflammation in rheumatoid disorders with tolerogenic nanoparticles

W.36 - Exploration of autophagic modulators of Aβ production for inactivating the targeted inflammasomes

F.98 - Fostamatinib, a Spleen Tyrosine Kinase (Syk) Inhibitor, for Treatment of Warm Antibody Autoimmune Hemolytic Anemia (wAIHA): Preliminary Results of the SOAR Phase 2, Multicenter, Open-Label Study

T.96 - Fostamatinib, an Oral Spleen Tyrosine Kinase (Syk) Inhibitor, in Adult Persistent/Chronic Immune Thrombocytopenia (ITP): Safety and Efficacy Results From Patients Who Converted From Placebo Onto the 049 Open-Label Extension Study

F.116 - Gene Therapy Trial for Rare, Severe Neuromuscular Disease: Preliminary Efficacy, Safety and Immunological Findings

F.10 - Identification of potent RORc inhibitors for the treatment of IL-17-mediated inflammatory diseases: is it worth the risk?

F.87 - In vitro and in vivo pharmacodynamic profile of DV281, a TLR9 agonist, in development as an inhalational therapeutic for lung cancer

T.1 - Monocyte NOTCH2 Expression Predicts Interferon-beta Immunogenicity in Multiple Sclerosis Patients

T.8 - Repairing Foxp3 mutations in scurfy T cells restores regulatory T cell function

T.113 - Retrovirus-derived Virus-Like Particles as tolerogenic vaccines for food allergy treatment

F.25 - BPX-501 cell infusion after alpha/beta T-cell and B-cell depleted HLA-haploidentical HSCT (haplo-HSCT) in children with primary immunodeficiencies (PIDs): high rate of cure with low risk of acute and chronic GvHD.

W.95 - Clonality and Function Of Cytomegalovirus Specific T Cells In Transplant Recipients

F.32 - Complement Induces Inflammasome Assembly in IFN-γ-primed Human Endothelium: Mechanisms and Consequences for Allograft Rejection

T.50 - CRISPR/Cas9-Mediated Ablation of Class I and II Major Histocompatibility Complex Antigen Expression on Human Endothelial Cells

F.24 - Durable Mixed Hematopoietic Chimerism through Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates across MHC-barriers

T.32 - Ex-vivo expansion of Regulatory T cells from long-term Belatacept-Treated Kidney Transplant Patients restores both their phenotype and in vitro suppressive function

W.50 - Generation of human/pig hybrid thymus to achieve immune tolerance to pig antigens with optimal immune function

F.9 - HCV-induced heterologous immunity regulates alloreactive T-cell exhaustion in liver transplantation

W.10 - Multiplexed Immunofluorescence to Investigate the Immune Response to BK Virus in Kidney Transplant Recipients

F.110 - Potential for Immunity and Tolerance after Bilateral Orthotopic Lung Transplant (BOLT) in Tandem with a CD3+/CD19+ Depleted Vertebral Bone Marrow Transplant (BOLT+BMT) from 1 of 8 HLA-Matched Cadaveric Donors

F.42 - Precision phenotyping of histologically stable kidney transplants

T.23 - Reshaping undesired immune reactivity by regulatory T cells - experience from kidney transplantation (One Study) and chromic GvHD (PegTreg)

W.80 - Virus specific T lymphocytes expansion for Adoptive Immunotherapy