Radiation and Cancer Physics

Panel 05 - NCI's Quantitative Imaging Network: Development and Integration of Novel Tools for Oncology Clinical Trials and Patient Management

10:45 AM - 12:15 PM
Location: Lila Cockrell Theatre

Session Type: Panel
1.50 AMA PRA Category 1 Credits™
1.50 CAMPEP Credits
1.50 MDCB Credits

The National Cancer Institute (NCI) has funded the Quantitative Imaging Network (QIN) since 2009 to develop novel approaches, including tool development, for quantitative imaging and clinical decision support in oncology. Multidisciplinary research teams from top institutions across the country that make up this network are developing a number of quantitative cancer imaging methods and tools that can be applied in unique ways to add value to the management of oncology patients. This session will feature QIN members that are developing and validating quantitative imaging tools for common cancers that are of interest to the membership of ASTRO. The panel will describe how advanced imaging modalities can complement more conventional ones for oncologic evaluations. There will be a particular focus on tools that are in an advanced stage of development with presentations that address unique clinical translational issues. Another focus will involve an overview of the computing architecture/pipelines and informatics tools needed to fully exploit the wealth of data that will be generated with increased utilization of advanced quantitative imaging techniques. This panel will raise awareness of the potential utility of advanced quantitative imaging for both research and general clinical practice. Several barriers have limited wider adoption of advanced quantitative imaging techniques in the clinic. We believe that panels such as the one proposed here will help educate oncologists about the value of quantitative imaging and further promote the development and validation of new tools and methods needed to more fully bring quantitative imaging into the clinical setting.

Learning Objectives:


Hui-Kuo George Shu, MD, PhD, FASTRO

Winship Cancer Institute of Emory University

Emory University, Dept. of Radiation Oncology: Professor: Employee

Varian Medical Systems: Honoraria, Speaker's Bureau, Travel Expenses

Apple: Stock; Medtronics: Stock

NCI-QIRT Working Group: Co-Chairman; QIN CTTDWG: Chairman; QIN EC: Co-Chairman

Hui-Kuo G. Shu, MD, PhD, is a professor in the Department of Radiation Oncology at Emory University. He received his BA in biology at Washington University in St. Louis, MO, in 1986 and MD/PhD in molecular biology at Case Western Reserve University in Cleveland, OH, in 1993. He completed of an internship in Internal Medicine at University Hospitals of Cleveland in 1994 and residency in Radiation Oncology at the University of California, San Francisco in 1999. He also completed a two year research fellowship at the Brain Tumor Research Center at UCSF. He has been a member of the Department of Radiation Oncology at Emory University since 2005.
Dr. Shu specializes in the treatment of CNS malignancies with radiation and has published extensively in these areas. He is actively involved many brain tumor clinical trials including as PI for investigator-initiated trials examining a novel histone deacetylase inhibitor for glioblastoma therapy and innovative use of volumetric modulated arc therapy for treatment of brain metastasis. Overall, he has published, as lead/senior author or co-author, more than 80 peer-reviewed manuscripts and 120 abstracts presented at national or international meetings. His most recent research interests have been in the development of spectroscopic magnetic resonance imaging (sMRI) for evaluating glioblastomas particularly focusing on its use to better guide radiation treatment planning for infiltrative disease not otherwise appreciated on standard MRI sequences. He is co-PI of the Emory Brain Tumor Imaging team that is funded by the National Institutes of Health (NIH) to develop sMRI for glioblastoma imaging as one of approximately 25 teams that make up the National Cancer Institute’s Quantitative Imaging Network (QIN). He is active in many professional/scientific societies including the American Society for Therapeutic Radiology and Oncology (ASTRO), the Radiological Society of North America (RSNA), the Society for Neuro-Oncology (SNO), among others.


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John Buatti, MD, FASTRO

University of Iowa: Professor and Chair Department of Radiation Oncology: Employee

Up to Date: Paid Royalty

John M. Buatti, MD, FASTRO, Professor and Chair, Department of Radiation Oncology, University of Iowa

Dr. Buatti is Professor and the Chair of the Department of Radiation Oncology, a position that he has held with distinction since 2001 when he established an independent department at the University of Iowa Hospitals and Clinics. In 2005, he opened Iowa’s first Center of Excellence in Image Guided Radiation Therapy, which was innovative for its use of advanced 3D imaging including a 3T MR scanner and 40 slice respiratory-gated PET/CT scanner to better locate and treat tumors. As a clinician, he is a leading authority on the treatment of cranial malignancies.
He is a prolific scholar having authored or co-authored more than 220 peer-reviewed publications. He has published 24 book chapters, and more than 170 abstracts.
With a life-long commitment to improve the quality of cancer imaging he served as the first chair of the Steering Committee for the Quantitative Imaging Network (QIN) and Chair of the Clinical Trials Design and Development Working Group and was a member of the Coordinating Committee for QIN. He has served on the ASTRO Education Committee, as Co-Chair of the ASTRO IHE-RO (Integrating Health Enterprise-Radiation Oncology) and served on the ASTRO Science Council Steering Committee. He is currently chairing an ASTRO task-force on Theranostics as well as a member of the ASTRO Nominating Committee.
He is and advocate for diversity in the workplace and encourages the development of scientist-investigators through summer internships and the active recruitment of minorities. His enthusiastic devotion to education is evident in his biography.


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Panel 05 - NCI's Quantitative Imaging Network: Development and Integration of Novel Tools for Oncology Clinical Trials and Patient Management

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