Radiation and Cancer Biology

EDU 25 (Live SA-CME) - Translational Genomics to Advance Precision Radiation Oncology

1:00 PM - 2:30 PM
Location: Room 006

Session Type: Educational
1.50 AMA PRA Category 1 Credits™
1.50 CAMPEP Credits
1.50 MDCB Credits

To receive Live SA-CME credit, you must add this session to your registration for an additional fee. For Live SA-CME credit you must present your ticket at the door and complete the online assessment. Space is limited, so please register early. Please note that events and fees are subject to change.


Large-scale genomics studies are transforming our understanding of tumor biology; however, despite a dramatic increase in available data, translating genomic findings to clinical practice remains a significant challenge. This session will focus on current efforts to leverage genomic data to advance clinical radiation oncology. Presentations will describe preclinical systems used in genomic analyses and will explain the biological and technical underpinnings of common genomic assays. All speakers are active translational investigators and will highlight different genomic platforms in current use, including DNA-based mutational and copy-number analyses, RNA-based gene expression analyses, and metabolic/proteomic approaches. We will examine several representative biomarkers in detail to highlight the path from biomarker discovery to clinical implementation. Finally, we will describe the challenges that exist when attempting to validate tumor genomic features as prognostic and/or predictive biomarkers, and we will highlight what we see as opportunities for on-going investigations that are unique to radiation oncology.

Learning Objectives:


Kent Mouw, MD, PhD

Brigham & Women's Hospital/Dana-Farber Cancer Inst: Instructor: Employee

Kent W Mouw, MD, PhD is a radiation oncology physician-scientist at Dana-Farber Cancer Institute/Brigham & Women's Hospital and an Instructor in Medicine at Harvard Medical School. He obtained his medical and graduate degrees from the University of Chicago and completed a radiation oncology residency in the Harvard Radiation Oncology Program and a post-doctoral research fellowship at Dana-Farber Cancer Institute. In addition to providing radiation oncology care for patients with genitourinary malignancies, Dr. Mouw oversees a basic and translational research laboratory that investigates the role of DNA repair pathway alterations in bladder cancer and other tumor types.


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EDU 25 (Live SA-CME) - Translational Genomics to Advance Precision Radiation Oncology

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