Biochemistry

Abstract

CS-1-6 - JAZ proteins mitigate the metabolic cost of plant defense against insect herbivores

Sunday, July 15
2:43 PM - 2:45 PM

The plant hormone jasmonate activates anti-insect defense responses that are metabolically costly and often linked to reduced growth. Although it is known that jasmonate exerts its effects by triggering the degradation of JASMONATE ZIM DOMAIN (JAZ) transcriptional repressor proteins, genetic redundancy within the JAZ family has hampered efforts to understand the biological consequences of unleashing the jasmonate response over extended developmental time scales. Here, we combined mutations within the 13-member Arabidopsis JAZ gene family to investigate the relationship between defense, growth, and reproduction under conditions of chronic JAZ depletion. A jaz decuple line (jazD) harboring mutations in ten JAZ genes exhibited hyper-resistance to attack by insect larvae, strongly reduced vegetative growth rate, and compromised seed production. Metabolic phenotypes of jazD discerned from global protein and transcript profiling were indicative of elevated carbon allocation to protein- and amino acid-based defense traits controlled by both the jasmonate-MYC and ethylene-ERF branches of immune signaling. The strong defense sink in jazD leaves was linked to increased respiration and hallmarks of carbon starvation, whereas area-based photosynthetic efficiency was unaffected. We propose that JAZ proteins flexibly adjust growth-defense conflict to match anticipated changes in resource availability, potentially avoiding the detrimental effects of carbon limitation that may arise during growth-to-defense transitions.


Co-Authors

Ian Major – Michigan State University Yuki Yoshida – The University of Tokyo Kun Wang – Michigan State University Koichi Sugimoto – Michigan State University George Kapali – Michigan State University Christoph Benning – Michigan State University Gregg Howe – Michigan State University

Qiang Guo, PhD

PhD student
Michigan State University

PhD student from Michigan State University (2013-current)
Advisor: Dr. Gregg Howe

Presentation(s):

Send Email for Qiang Guo


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CS-1-6 - JAZ proteins mitigate the metabolic cost of plant defense against insect herbivores



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