Biotic Stress/Applied Plant Bio


CS-3-1 - Extracellular vesicles: key mediators of plant-microbe interactions?

Sunday, July 15
1:03 PM - 1:23 PM

Exosomes are extracellular vesicles (EVs) that play a central role in intercellular signaling in mammals by transporting proteins and small RNAs. Plants are also known to produce EVs, particularly in response to pathogen infection. Our laboratory has developed methods for purifying EVs from plant leaves and are now characterizing their contents. These analyses have revealed that plant EVs are highly enriched in proteins involved in biotic and abiotic stress responses, and carry miRNAs and siRNAs. In addition, EV secretion is enhanced in plants infected with Pseudomonas syringae and in response to treatment with salicylic acid Recent work has established that EVs are rapidly taken up by filamentous pathogens from host plants and in vitro. These findings suggest that EVs represent an important component of the plant immune system. In this talk I will present our ongoing investigations into the possible functions of EVs, and our initial investigations into the genetic requirements for EV biosynthesis.



Brian Rutter – Indiana University

Roger W. Innes, PhD

Indiana University

Roger Innes holds the Class of 1954 Professorship in Biology at Indiana University-Bloomington, and currently directs IUB’s Electron Microscopy Center. He received his Ph.D. in Molecular, Cellular and Developmental Biology at the University of Colorado-Boulder, and completed Post-doctoral research at the University of California-Berkeley. He is an elected fellow of the American Association for the Advancement of Science and the American Academy of Microbiology. Dr. Innes’ research focuses on the immune system in plants, with a particular interest in how plants detect pathogens and how detection is translated into an active immune response. His group was among the first to identify and clone plant disease resistance genes using the model plant Arabidopsis thaliana. In a second area of research, the Innes laboratory has been investigating intracellular and intercellular signaling and cell biology of the plant immune system, including analysis of endomembrane trafficking in plant cells and production of extracellular vesicles.


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