Category: Federal Forum Posters
Purpose: Spontaneous bacterial peritonitis (SBP) is a complication of cirrhosis that may lead to hospital admission. The mortality rate of patients with cirrhosis increases after the first occurrence of SBP, additionally, there is a high risk for recurrence after a first episode. Primary prophylaxis is indicated in patients considered “high risk” for the development of SBP and is an important intervention to improve outcomes in cirrhotic patients. The aim of this project is to review our institution’s implementation of guideline recommendations for the primary prophylaxis of SBP.
Methods: This study is a retrospective review of inpatient paracentesis results to determine if the results met criteria for SBP primary prophylaxis and whether prophylaxis was initiated at that time. The criteria for indication of primary prophylaxis includes low ascitic fluid total protein with renal and/or severe hepatic impairment, or previous variceal hemorrhage/gastrointestinal bleed. We plan to follow-up with the same patients the subsequent year and determine if they later had a diagnosis of SBP.
The primary outcome will assess the number of paracentesis results at our institution that met criteria and in which SBP primary prophylaxis was appropriately initiated. The secondary outcome will assess the number of patients who met criteria, did not receive SBP primary prophylaxis, and later developed SBP.
Results: not applicable
Conclusion: not applicable
Taylor Blevins– PGY1 Pharmacy Practice Resident, South Texas Veterans Health Care System, San Antonio, TX