Category: Federal Forum Posters
Purpose: Literature has shown that appropriate renal dosing of medications will not decrease efficacy but rather will decrease the risk of side effects. Pharmacists can review patient-specific factors to adjust medications according to renal function and make appropriate dose adjustments. The purpose of this study is to evaluate the safety outcomes of a pharmacist-led renal dosing protocol on the dosing of renally cleared medications.
Methods: This retrospective chart review will include patients admitted to acute medical floors at a Veterans Affairs Medical Center who were prescribed medications on the hospital’s renal dosing protocol. The renal dosing protocol was implemented in the inpatient pharmacy in 2013. The protocol is pharmacist-driven and includes 65 medications that are eligible to be renally adjusted at order verification. Patients who received one of the medications on the renal dosing protocol between 2011-2015 are eligible for inclusion. Patients will be excluded if they received antibiotics that were ordered by Clinical Pharmacy Specialists with scope of practice, as the medication would be renally dosed by a pharmacist when it was ordered. Baseline demographics, including age, gender, height, weight, and serum creatinine levels, will be collected for each patient. The primary endpoint is to determine the impact dosing interventions made on adverse outcomes experienced by patients. Secondary endpoints will include the appropriateness of the dosing change and cost-savings associated with the change. All data will be recorded without patient identifiers and maintained in a confidential and secured electronic file.
Results: not applicable
Conclusion: not applicable
Allison Lizer– PGY1 Pharmacy Resident, Martinsburg VA Medical Center, Winchester, VA