Category: Federal Forum Posters
Purpose: Central hemodynamics have been purported to be superior cardiovascular disease risk predictors. This investigation will do a prospective evaluation of central hemodynamic parameters and cognitive function. The primary objective is to determine the predictive relationship between central systolic blood pressure on cognitive impairment.
Methods: Patients 18 years of age or older will complete a health questionnaire and the ACEmobile cognition test. Central hemodynamic measurements will be performed using the non-invasive SphygmoCor XCEL system. The primary location for data collection will be at David Grant Medical Center (DGMC), Travis Air Force Base, California. The questionnaire will obtain the following information: date of birth, Department of Defense identification number, race/ethnicity, gender, level of education, comorbidities, and medications. The ACEmobile will be used as it comprises more cognitive domains than the Mini-Mental State Examination and is an electronic version to help reduce error rates. The SphygmoCor XCEL system will be utilized to collect the following data: brachial and central systolic and diastolic blood pressures, mean pressure, and augmentation index among many other variables. This data will be transferred to a Common Access Card enabled computer in Microsoft Excel format. Analyses will be performed accordingly depending on the endpoint of interest. All data will be collected over 4 months and be de-identified at the end of the study period. Data will be analyzed using descriptive statistics with a correlation coefficient calculated for the relationship between central systolic blood pressure and ACEmobile score.
Results: Not applicable
Conclusion: Not applicable
Brad Driscoll– AFIT Pharmacy Resident, UASF, Fairfield, CA