Category: Federal Forum Posters
Purpose: The purpose of this retrospective Medication Use Evaluation (MUE) is to review the appropriate utilization of pharmacotherapy used to treat Veterans diagnosed with alcohol use disorder (AUD) at Bay Pines Veterans Affairs Healthcare System (BPVAHCS). First line Food and Drug Administration approved pharmacotherapies include naltrexone (oral or intramuscular injection), disulfiram, and acamprosate. Currently, there is a lack of data available to recommend using one of these first-line medications over another. With the numerous number of Veterans affected by AUD, it is imperative to determine if these agents are being selected and used appropriately.
Methods: A retrospective chart review will be conducted to review patients at BPVAHCS treated for AUD using at least one first line medication indicated for AUD between September 2016 to September 2017. Exclusion criteria includes veterans being treated with these agents having no diagnosis of AUD and patients being treated for AUD with either gabapentin, topiramate, or both. De-identified data for a maximum of two hundred patients will be reviewed. A Veterans Integrative Service Network (VISN) 8 data manager will pull data for the specified date range using the AUD dashboard patient parameters. Data will first be collected to determine the appropriate use of each study medication based on Veteran Alcohol Use Disorder Identification Test (AUDIT-C) scores, medication criteria for use, and contraindications.
Data may be reviewed to determine the effectiveness of AUD pharmacotherapy, if available, including a review of hospital admissions, urine drug screen/breathalyzer results, naltrexone clinic appointments, refill history, documented self-reported information from patients, average length of treatment, patient retention, and non-pharmacological therapy. Tolerability may also be assessed through chart reviews focusing on liver function tests, serum creatinine levels, documented side effects, changes in AUD pharmacotherapy, and number of drop outs if available.
Results: Not applicable
Conclusion: Not applicable
Bionqua Lynch– Pharmacy Resident, Bay Pines VA Healthcare System, Largo, FL