Category: Federal Forum Posters
Purpose: The purpose of this medication use evaluation is to assess the adherence to recommended Clostridium difficile management in concordance with the Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) in Veterans admitted to Bay Pines VA Healthcare System.
Methods: Veterans who were admitted to Bay Pines VA Healthcare System and were tested for Clostridium difficile (CDI) infection from June 2018-August 2018 will serve as the medication use evaluation sample population. A chart review will be conducted and data will be extracted including patient demographics, presence of antibiotic allergies, number of unformed stools in the 24 hours prior to testing, characteristics of stools, Clostridium difficile test results (glutamate dehydrogenase (GDH), presence of toxin, nucleic acid amplification test (NAAT) if available), retesting within 7 days during the same episode of diarrhea, test for cure, broad spectrum antibiotics within 90 days of Clostridium difficile testing, concurrent infection, concurrent non-CDI antibiotics and duration, concurrent use of cholestyramine, inpatient dietary order, immunocompromised status, white blood cell (WBC) count, serum creatinine (SCr) level, albumin, temperature, presence of hypotension (as defined by systolic blood pressure less than 90 mmHg), septic shock, ileus, or toxic megacolon, number of CDI reoccurrence, prior Clostridium difficile treatment regimen with duration, current treatment regimen with duration, prescribing provider, and achievement of clinical cure. Utilizing collected data, this medication use evaluation will determine the proportion of patients managed in concordance with the most recent treatment guidelines.
Results: not applicable
Conclusion: not applicable
Samuel Solone– PGY1 Pharmacy Resident, Bay PInes VA Healthcare System, Clearwater, FL