Category: Federal Forum Posters
Purpose: Concomitant administration of direct oral anticoagulants (DOACs) and non-steroidal anti-inflammatory drugs (NSAIDs) can increase the risk of a hemorrhagic event. The risk of inflammation is elevated in patients with cardiac disease, making concomitant use even more probable. The objective of this review is to assess the utilization of concomitant oral anticoagulants and NSAIDs and incidence of adverse events in this patient population at the Bay Pines VA Healthcare System.
Methods: This medication utilization review was evaluated by the Bay Pines VA Healthcare System Research and Development Service and was deemed a quality improvement project. A retrospective chart review will be done of up to 200 patients with an active prescription for DOACs and NSAIDs in August 2018. Collected information will be maintained in an excel spreadsheet format and stored securely in the pharmacy residency group drive. Information will be collected on any adverse events occurring with concomitant use of DOACs and NSAIDs. Exclusion criteria for this review will include Veterans with an indication of prophylaxis for venous thromboembolism and pulmonary embolism, treatment with low dose aspirin (81 mg), expired or discontinued NSAID prescriptions, or death due to any cause.
Results: Not applicable
Conclusion: Not applicable
Quratulain Zulfiqar– PGY1 Pharmacy Resident, Bay Pines VA Healthcare System, St. Petersburg