Category: Federal Forum Posters
Purpose: This study aims to compare outcomes associated with various diagnostic and treatment methods in inpatients with diabetic foot infections. Diabetic foot infections with osteomyelitis often require amputations, and sometimes even serial amputations due to inadequate initial intervention and progression of infection. It is thought that the use of magnetic resonance imaging (MRI) will improve outcomes and need for repeat surgical intervention and repeat antibiotic courses. Data will be collected to identify diagnostic and treatment methods to improve overall outcomes in patients diagnosed with DFI.
Methods: This retrospective cohort study will include patients greater than or equal to 18 years of age with a diabetic foot infection as identified via ICD9 and ICD 10 codes. Time period of patients to be studied is January 2005 to December 2016. Baseline characteristics will be collected for all patients. Subgroup analysis of outcomes based on treatment modality will be performed. Multivariate regression analysis, stratified by DFI severity score, will be performed to analyze impact of comorbid conditions, treatment variables, and baseline characteristics on the primary outcome. Significant factors will be built into a multivariate logistic regression analysis to determine if MRI reduces subsequent amputation and antibiotic use. Factors will be eliminated based on lack of significance in a backwards fashion until a stable model is formed. This study has been submitted to the Institutional Review Board of the WNY VA and is pending approval.
Results: not applicable
Conclusion: not applicable
Michael Carter– Pharmacy Resident, VA Western NY Healthcare System, Buffalo, NY