The same diet and exercise regime prescribed for type 1 polysaccharide storage myopathy (PSSM1) is recommended for type 2 PSSM (PSSM2); however treatment responses have not been documented for PSSM2. A retrospective case-control questionnaire (2008-2016) was used to capture clinical signs of PSSM2 in Warmblood horses (WB) (n = 42), before and after a recommended low nonstructural carbohydrate/fat supplemented diet and exercise regimen. Twenty-two owners of healthy control WB also provided information. Muscle glycogen concentrations were measured fluorometrically in PSSM2 WB (n = 36) to determine if they were abnormally elevated compared to horses with no myopathy (n = 23). Significantly more PSSM2 WB had performance decline and a reluctance to collect than control WB. With diet and exercise recommendations, 80% of PSSM2 WB owners reported improvement in clinical signs; however, 53% of horses were not advancing as expected in training with reluctance to go forward and collect persisting in approximately one third of horses. Glycogen concentrations in PSSM2 WB were variable and the median was not significantly different from WB with no histopathology. In conclusion, diet and exercise recommendations ideal for PSSM1 may improve but not eliminate clinical signs of PSSM2 in WB. Glycogen concentrations in many PSSM2 WB are not abnormally elevated.
Michigan State University, College of Veterinary Medicine
Zoë graduated from the University of California at Davis with a Bachelor of Science in cell biology and a minor in animal science with an equine emphasis. Currently, Zoë has finished her second year of veterinary school at Michigan State University and will start her PhD this fall as a dual degree student. She has a strong research interest in equine neuromuscular disorders and is mentored by Dr. Stephanie Valberg.
Thursday, June 14
11:30 AM – 11:45 AM
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